Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.65 |
| ▸ | CTSK | P43235 | 15/20 | 0.65 |
| ▸ | CTSL | P07711 | 14/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3011051 | 0.87 | CTSS (0.85) | CTSSCTSKCTSL | |
| SCHEMBL3011049 | 0.87 | CTSS (0.85) | CTSSCTSKCTSL | |
| SCHEMBL13316433 | 0.81 | CTSS (0.88) | CTSSCTSKCTSL | |
| SCHEMBL6688065 | 0.80 | CTSS (0.51) | CTSSCTSKCTSL | |
| SCHEMBL3837643 | 0.80 | CTSS (0.81) | CTSSCTSKCTSL | |
| SCHEMBL3023782 | 0.79 | CTSS (1.00) | CTSSCTSKCTSL | |
| SCHEMBL3007162 | 0.79 | CTSS (0.82) | CTSSCTSKCTSL | |
| SCHEMBL3023781 | 0.79 | CTSS (1.00) | CTSSCTSKCTSL | |
| SCHEMBL3007161 | 0.79 | CTSS (0.82) | CTSSCTSKCTSL | |
| SCHEMBL3839692 | 0.78 | CTSS (0.81) | CTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658267-A4 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2007-08-01 | — | — | EP | disclosed |
| EP-1658267-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005034848-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2005-04-21 | — | — | WO | disclosed |