Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.51 |
| ▸ | CTSL | P07711 | 16/20 | 0.51 |
| ▸ | CTSK | P43235 | 11/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4800085 | 0.85 | CTSS (0.69) | CTSSCTSLCTSK | |
| SCHEMBL4800065 | 0.85 | CTSS (0.69) | CTSSCTSLCTSK | |
| SCHEMBL4800071 | 0.85 | CTSS (0.69) | CTSSCTSLCTSK | |
| SCHEMBL5499097 | 0.84 | CTSS (0.48) | CTSSCTSLCTSKKDM4EALDH1A1 | |
| SCHEMBL5841440 | 0.83 | CTSS (0.64) | CTSSCTSLCTSKKDM4EALDH1A1 | |
| SCHEMBL5841433 | 0.83 | CTSS (0.64) | CTSSCTSLCTSKKDM4EALDH1A1 | |
| SCHEMBL6688343 | 0.82 | CTSS (0.55) | CTSSCTSLCTSK | |
| SCHEMBL6685701 | 0.81 | CTSS (0.53) | CTSSCTSLCTSK | |
| SCHEMBL5497850 | 0.80 | CTSS (0.65) | CTSSCTSLCTSK | |
| SCHEMBL3022159 | 0.79 | CTSS (0.68) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |