Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 9/20 | 0.45 |
| ▸ | THRB | P10828 | 9/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5278943 | 0.87 | THRA (0.45) | THRATHRBCA1CA2 | |
| SCHEMBL4351634 | 0.81 | THRA (0.47) | THRATHRBHIF1A | |
| SCHEMBL4530357 | 0.81 | THRA (0.71) | THRATHRB | |
| SCHEMBL4360460 | 0.77 | THRA (0.50) | THRATHRBHIF1A | |
| SCHEMBL4361873 | 0.75 | THRA (0.48) | THRATHRBHIF1A | |
| SCHEMBL4558891 | 0.74 | THRA (0.50) | THRATHRB | |
| SCHEMBL4351938 | 0.72 | THRB (0.45) | THRATHRBHIF1A | |
| SCHEMBL14383356 | 0.72 | THRA (0.67) | THRATHRB | |
| SCHEMBL5279235 | 0.71 | THRA (0.66) | THRATHRB | |
| SCHEMBL13708075 | 0.70 | THRB (0.65) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537073-B1 | BENZAMIDE OR PHENYLACETAMIDE DERIVATIVES USEFUL AS THYROID RECEPTOR LIGANDS | KAROBIO AB (SE) | 2007-09-12 | — | — | EP | claimed |