Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | PTGIR | P43119 | 1/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13498610 | 1.00 | CA1 (0.55) | CA1CA2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18461191 | 0.94 | SMN1; SMN2 (0.54) | CA1CA2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL19214417 | 0.90 | ALDH1A1 (0.51) | CA1CA2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL12561798 | 0.88 | CARM1 (0.52) | CA1CA2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL17204382 | 0.84 | CA1 (0.51) | CA1CA2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL23928027 | 0.83 | CARM1 (0.48) | CA1CA2MAPTESR2RAB9A | |
| SCHEMBL13498612 | 0.83 | RAB9A (0.50) | CA1CA2MAPTALDH1A1ESR2 | |
| SCHEMBL14665431 | 0.83 | CARM1 (0.48) | CA1CA2ESR2RAB9APARP15 | |
| SCHEMBL11843612 | 0.83 | RAB9A (0.50) | CA1CA2MAPTALDH1A1ESR2 | |
| SCHEMBL19407121 | 0.83 | MAPT (0.63) | MAPTSMN1; SMN2ALDH1A1ESR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740545-A1 | PROCESS FOR MAKING MONTELUKAST AND INTERMEDIATES THEREFOR | Synthon B.V. (NL) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105750-A1 | PROCESS FOR MAKING MONTELUKAST AND INTERMEDIATES THEREFOR | SYNTHON B.V. (NL) | 2005-11-10 | — | — | WO | disclosed |
| US-3975429-A | Cyclopropanemethyl esters of cinnamic acid and derivatives thereof | ZOECON CORPORATION (US) | 1976-08-17 | — | — | US | disclosed |