Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493607 | 0.85 | KDM4E (0.52) | KDM4EALDH1A1KMT2ATDP1BCHE | |
| SCHEMBL5813773 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1KMT2ATDP1BCHE | |
| SCHEMBL4273025 | 0.81 | ALDH1A1 (0.61) | KDM4EALDH1A1KMT2ATDP1APP | |
| SCHEMBL4273021 | 0.81 | ALDH1A1 (0.61) | KDM4EALDH1A1KMT2ATDP1APP | |
| SCHEMBL3121290 | 0.80 | KDM4E (0.97) | KDM4EALDH1A1KMT2ATDP1BCHE | |
| SCHEMBL3121297 | 0.80 | KDM4E (0.97) | KDM4EALDH1A1KMT2ATDP1BCHE | |
| SCHEMBL5494854 | 0.78 | MAOB (0.66) | KDM4EALDH1A1KMT2AMAOAMAOB | |
| SCHEMBL29359315 | 0.77 | TRPV1 (0.67) | KDM4EALDH1A1KMT2AMAOAMAOB | |
| SCHEMBL14255225 | 0.77 | KDM4E (0.81) | KDM4EALDH1A1KMT2ATDP1BCHE | |
| SCHEMBL16274617 | 0.77 | KDM4E (0.81) | KDM4EALDH1A1KMT2ATDP1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073860-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-07-07 | — | — | US | claimed |
| US-20140073595-A1 | AROMATIC AMIDES AS POTENTIATORS OF BIOEFFICACY OF ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-03-13 | — | — | US | claimed |
| US-8580752-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTITIC AND INDUSTRIAL RESEARCH (IN) | 2013-11-12 | — | — | US | claimed |
| US-20070004645-A1 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-01-04 | — | — | US | claimed |
| WO-2006103527-A1 | AROMATIC SUBSTITUTED PENTADIENOIC ACID AMIDE FOR COMBINATION WITH ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-10-05 | — | — | WO | claimed |
| US-9073860-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-07-07 | — | — | US | disclosed |
| US-20140073595-A1 | AROMATIC AMIDES AS POTENTIATORS OF BIOEFFICACY OF ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-03-13 | — | — | US | disclosed |
| US-8580752-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTITIC AND INDUSTRIAL RESEARCH (IN) | 2013-11-12 | — | — | US | disclosed |
| US-20070004645-A1 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073595-A1 | AROMATIC AMIDES AS POTENTIATORS OF BIOEFFICACY OF ANTI-INFECTIVE DRUGS | DDC, APEH, AADAC | KDM4E 1523/4885ALDH1A1 265/4885KMT2A 4113/4885 |
| US-20070004645-A1 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | DDC, APEH, AADAC | KDM4E 1523/4885ALDH1A1 265/4885KMT2A 4113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.