Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499269 | 0.82 | L3MBTL1 (0.39) | L3MBTL1L3MBTL3KMT2AMEN1HDAC1 | |
| SCHEMBL2861902 | 0.76 | PER2 (0.40) | L3MBTL1L3MBTL3KMT2AMEN1HDAC1 | |
| SCHEMBL2855569 | 0.75 | L3MBTL1 (0.39) | L3MBTL1L3MBTL3KMT2AMEN1HDAC1 | |
| SCHEMBL20267398 | 0.73 | KMT2A (0.64) | KMT2AMEN1GAACASP3SENP7 | |
| SCHEMBL11476095 | 0.72 | KMT2A (0.67) | KMT2AMEN1GAACASP3SENP7 | |
| SCHEMBL11236018 | 0.69 | KMT2A (0.50) | KMT2AMEN1CASP3SENP7NPC1 | |
| SCHEMBL14775292 | 0.69 | KMT2A (0.46) | L3MBTL1L3MBTL3KMT2AMEN1KDM4E | |
| SCHEMBL29989872 | 0.68 | KMT2A (0.41) | L3MBTL1L3MBTL3KMT2AMEN1KDM4E | |
| SCHEMBL5982426 | 0.67 | ADORA2A (0.36) | GAA | |
| SCHEMBL20267432 | 0.67 | KMT2A (0.68) | KMT2AMEN1KDM4EGAACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748985-A1 | CYCLIC AMIDE DERIVATIVES, AND THEIR PRODUCTION AND USE AS ANTITHROMBOTIC AGENTS | Takeda Pharmaceutical Company Limited (JP) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005113504-A1 | CYCLIC AMIDE DERIVATIVES, AND THEIR PRODUCTION AND USE AS ANTITHROMBOTIC AGENTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-12-01 | — | — | WO | disclosed |