Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PEPD | P12955 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3009795 | 1.00 | FKBP1A (0.54) | FKBP1APOLBRAB9APEPDALDH1A1 | |
| SCHEMBL3009794 | 1.00 | FKBP1A (0.54) | FKBP1APOLBRAB9APEPDALDH1A1 | |
| SCHEMBL19334646 | 0.89 | FKBP1A (0.50) | FKBP1APOLBRAB9APEPDALDH1A1 | |
| SCHEMBL20123372 | 0.87 | POLB (0.50) | FKBP1APOLBRAB9APEPDALDH1A1 | |
| SCHEMBL1976765 | 0.87 | POLB (0.50) | FKBP1APOLBRAB9APEPDALDH1A1 | |
| SCHEMBL3231642 | 0.87 | FKBP1A (0.51) | FKBP1APOLBRAB9APEPDALDH1A1 | |
| SCHEMBL5727740 | 0.86 | FKBP1A (0.48) | FKBP1APOLBRAB9APEPDXPNPEP1 | |
| SCHEMBL8141816 | 0.86 | FKBP1A (0.48) | FKBP1APOLBRAB9APEPDXPNPEP1 | |
| SCHEMBL3656325 | 0.86 | FKBP1A (0.48) | FKBP1APOLBRAB9APEPDXPNPEP1 | |
| SCHEMBL30599979 | 0.86 | POLB (0.58) | FKBP1APOLBRAB9APEPDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686201-A1 | INFLUENZA VIRUS REPLICATION INHIBITOR AND USE THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2020-07-29 | — | — | EP | disclosed |
| WO-2019052565-A1 | INFLUENZA VIRUS REPLICATION INHIBITOR AND USE THEREOF | 广东东阳光药业有限公司 | 2019-03-21 | — | — | WO | disclosed |
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |
| US-20170349587-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2017-12-07 | — | — | US | disclosed |
| US-9758515-B2 | Substituted polycyclic carbamoyl pyridone derivative prodrug | SHIONOGI & CO., LTD. (JP) | 2017-09-12 | — | — | US | disclosed |
| US-9388205-B2 | Ni complex and its derivatives, producing method, and the use thereof as an antioxidant | NATIONAL TAIWAN NORMAL UNIVERSITY (TW) | 2016-07-12 | — | — | US | disclosed |
| US-9388205-B2 | Ni complex and its derivatives, producing method, and the use thereof as an antioxidant | NATIONAL TAIWAN NORMAL UNIVERSITY (TW) | 2016-07-12 | — | — | US | disclosed |
| EP-2438989-B1 | USE OF ASYMMETRIC HYDROGENATION CATALYST | TAKASAGO PERFUMERY CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-9061959-B2 | Method for manufacturing optically active menthol | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-06-23 | — | — | US | disclosed |
| US-20150111854-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2015-04-23 | — | — | US | disclosed |
| US-7547718-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-06-16 | — | — | US | disclosed |
| US-7544706-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-06-09 | — | — | US | disclosed |
| US-20080125473-A1 | SUBSTITUTED IMIDAZOLES | PFIZER LIMITED (GB) | 2008-05-29 | — | — | US | disclosed |
| US-20080119536-A1 | SUBSTITUTED IMIDAZOLES | PFIZER LIMITED (GB) | 2008-05-22 | — | — | US | disclosed |
| US-20070276142-A1 | Catalytic Asymmetric Synthesis of Optically Active Alpha-Halo-Carbonyl Compounds | CHEMINOVA A/S (DK) | 2007-11-29 | — | — | US | disclosed |
| US-20070276142-A1 | Catalytic Asymmetric Synthesis of Optically Active Alpha-Halo-Carbonyl Compounds | CHEMINOVA A/S (DK) | 2007-11-29 | — | — | US | disclosed |
| US-20070276142-A1 | Catalytic Asymmetric Synthesis of Optically Active Alpha-Halo-Carbonyl Compounds | CHEMINOVA A/S (DK) | 2007-11-29 | — | — | US | disclosed |
| US-20070249526-A1 | PROCESS FOR THE PREPARATION OF CYCLIC PEPTIDES | ABBENANTE GIOVANNI | 2007-10-25 | — | — | US | disclosed |
| US-20070167506-A1 | SUBSTITUTED IMIDAZOLES | PFIZER INC. (US) | 2007-07-19 | — | — | US | disclosed |
| US-20050119167-A1 | Process for the preparation of cyclic peptides | THE UNIVERSITY OF QUEENSLAND (AU) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125473-A1 | SUBSTITUTED IMIDAZOLES | ABL1, TYR, CYP3A4 | FKBP1A 1664/4885POLB 3099/4885RAB9A 777/4885 |
| US-20150111854-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | PREP, UNG, DPP4 | FKBP1A 995/4885POLB 292/4885RAB9A 3863/4885 |
| US-20070276142-A1 | Catalytic Asymmetric Synthesis of Optically Active Alpha-Halo-Carbonyl Compounds | CBR1, CBR3, HAO1 | FKBP1A 1901/4885POLB 197/4885RAB9A 1954/4885 |
| US-20050119167-A1 | Process for the preparation of cyclic peptides | C3AR1, C5AR1, C9 | FKBP1A 2918/4885POLB 3610/4885RAB9A 3018/4885 |
| US-20070249526-A1 | PROCESS FOR THE PREPARATION OF CYCLIC PEPTIDES | C3AR1, C5AR1, C9 | FKBP1A 2918/4885POLB 3610/4885RAB9A 3018/4885 |
| US-20070167506-A1 | SUBSTITUTED IMIDAZOLES | ABL1, TYR, CYP3A4 | FKBP1A 1664/4885POLB 3099/4885RAB9A 777/4885 |
| US-20080119536-A1 | SUBSTITUTED IMIDAZOLES | ABL1, TYR, CYP3A4 | FKBP1A 1664/4885POLB 3099/4885RAB9A 777/4885 |
| US-20170349587-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | PREP, UNG, DPP4 | FKBP1A 995/4885POLB 292/4885RAB9A 3863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.