Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.60 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.60 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.60 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.45 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KDM5C | P41229 | 2/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL1405542 | 1.00 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL1405354 | 1.00 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL1405292 | 1.00 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL30553879 | 1.00 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL193677 | 0.89 | GPR84 (0.59) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Adipic Acid SCHEMBL1906615 | 0.88 | LMNA (0.65) | LMNAOR51E2CAMK2ASLC22A6TSHR | |
| Adipic Acid SCHEMBL28899127 | 0.88 | LMNA (0.65) | LMNAOR51E2CAMK2ASLC22A6TSHR | |
| Adipic Acid SCHEMBL722973 | 0.88 | LMNA (0.65) | LMNAOR51E2CAMK2ASLC22A6TSHR | |
| Glutarate SCHEMBL28137348 | 0.88 | SLC22A6 (0.65) | LMNAEGLN1ALKBH5SUCNR1CAMK2A | |
| SCHEMBL2762243 | 0.88 | CAMK2A (0.48) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119799397-A | Long-life SN-grade gasoline engine oil composition and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-119307297-A | Copper-nickel alloy friction film base wind power gear oil additive composition and preparation method thereof | 河南大学 | 2025-01-14 | — | — | CN | claimed |
| CN-115975705-B | Gasoline engine oil composition and preparation method thereof | 中国石油化工股份有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-115975702-B | Gasoline engine oil composition and preparation method thereof | 中国石油化工股份有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-117801854-A | Fuel oil detergent composition and preparation method thereof | 比亚迪股份有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117264654-A | Novel ethylene cracking coke inhibitor and preparation method and application thereof | 金浦新材料股份有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-115992027-A | Gasoline engine oil composition and preparation method thereof | 中国石油化工股份有限公司 | 2023-04-21 | — | — | CN | claimed |
| CN-115975702-A | Gasoline engine oil composition and preparation method thereof | 中国石油化工股份有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115975705-A | Gasoline engine oil composition and preparation method thereof | 中国石油化工股份有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115404118-A | Aluminum shell stretching oil composition | 季华实验室 | 2022-11-29 | — | — | CN | claimed |
| CN-113980252-A | Continuous production method of modified poly (butylene succinate) | 上海师范大学 | 2022-01-28 | — | — | CN | claimed |
| CN-103409177-B | Methanol fuel oil for ships and preparation method thereof | HU RONGHAN | 2015-03-04 | — | — | CN | claimed |
| CN-103409177-A | Methanol fuel oil for ships and preparation method thereof | HU RONGHAN | 2013-11-27 | — | — | CN | claimed |
| CN-103153276-A | Cosmetic composition comprising a supramolecular compound capable of establishing hydrogen bonds, and a particular oil | OREAL | 2013-06-12 | — | — | CN | claimed |
| CN-101617998-A | Cosmetic or dermatological composition comprising a compound capable of creating hydrogen bonds, and cosmetic treatment method | OREAL | 2010-01-06 | — | — | CN | claimed |
| CN-120924330-A | Lubricating oil composition for gas engine and preparation method thereof | 中国石油化工股份有限公司 | 2025-11-11 | — | — | CN | disclosed |
| CN-115806681-B | High-melting-point oxidized polyethylene wax microemulsion and preparation method thereof | 上海雅运科技有限公司 | 2025-05-30 | — | — | CN | disclosed |
| US-5514292-A | FOR USE WITH REFRIGERANTS, EPOXY CONTAINING PHOSPHONATE | TONEN CORPORATION (JP) | 1996-05-07 | — | — | US | disclosed |
| CN-85102007-A | COMPOUNDING RECIPE OF ADDITIVES FOR INTERNAL COMBUSTION ENGINE OIL | — | 1987-02-04 | — | — | CN | disclosed |
| US-4157261-A | PHOTOINITIATOR, CHLORINATED POLYOLEFIN BINDER | FUJI PHOTO FILM CO., LTD. (JP) | 1979-06-05 | — | — | US | disclosed |