Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.37 |
| ▸ | RXRG | P48443 | 3/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | HNF4A | P41235 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7583942 | 0.81 | RARG (0.32) | RXRARARARARBRARGHNF4A | |
| SCHEMBL5491284 | 0.78 | RXRA (0.35) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7584313 | 0.74 | MAOB (0.41) | — | |
| SCHEMBL5860140 | 0.71 | PPARG (0.56) | RXRARXRBRXRGPPARGCYP26A1 | |
| SCHEMBL7579554 | 0.71 | MAOB (0.49) | — | |
| SCHEMBL4446990 | 0.70 | RXRA (0.36) | RXRARXRBRXRGRARARARB | |
| SCHEMBL4070480 | 0.70 | LTA4H (0.34) | — | |
| SCHEMBL5364822 | 0.69 | RXRA (0.48) | RXRARXRBRXRGRARARARB | |
| SCHEMBL16316083 | 0.68 | RXRA (0.47) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6476127 | 0.68 | RXRA (0.47) | RXRARXRBRXRGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1576089-A4 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS | GAMIDA CELL LTD (IL) | 2007-02-14 | — | — | EP | disclosed |
| EP-1601759-A4 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS USING MODULATORS OF PI 3-KINASE | GAMIDA CELL LTD (IL) | 2007-02-14 | — | — | EP | disclosed |
| EP-1601759-A2 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS USING MODULATORS OF PI 3-KINASE | Gamida Cell Ltd. (IL) | 2005-12-07 | — | — | EP | disclosed |
| EP-1601759-A3 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS USING MODULATORS OF PI 3-KINASE | Gamida Cell Ltd. (IL) | 2005-10-27 | — | — | EP | disclosed |
| EP-1587779-A1 | 5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL 2,6-DIFLUOROHEPTATRIENOIC ACID DERIVATIVES HAVING SERUM GLUCOSE REDUCING ACTIVITY | Allergan, Inc. (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1576089-A2 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS | Gamida Cell Ltd. (IL) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004078917-A2 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS USING MODULATORS OF PI 3-KINASE | GAMIDA-CELL LTD. (IL) | 2004-09-16 | — | — | WO | disclosed |
| WO-2004065345-A1 | 5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL 2,6-DIFLUOROHEPTATRIENOIC ACID DERIVATIVES HAVING SERUM GLUCOSE REDUCING ACTIVITY | ALLERGAN, INC. (US) | 2004-08-05 | — | — | WO | disclosed |
| WO-2003062369-A2 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS | GAMIDA-CELL LTD. (IL) | 2003-07-31 | — | — | WO | disclosed |