Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875715 | 0.82 | MAPT (0.55) | MAPTCYP1A2CTSAALDH1A1APLNR | |
| SCHEMBL31264286 | 0.82 | MAPT (0.55) | MAPTCYP1A2CTSAALDH1A1APLNR | |
| SCHEMBL594691 | 0.81 | GRM5 (0.44) | MAPTCYP1A2HPGDSALDH1A1GABRP | |
| SCHEMBL31746517 | 0.81 | GRM5 (0.44) | MAPTCYP1A2HPGDSALDH1A1GABRP | |
| SCHEMBL946380 | 0.79 | P2RX7 (0.50) | MAPTCYP1A2HPGDSALDH1A1GABRP | |
| SCHEMBL32315381 | 0.79 | P2RX7 (0.50) | MAPTCYP1A2HPGDSALDH1A1GABRP | |
| SCHEMBL106420 | 0.79 | APLNR (0.50) | CTSAALDH1A1APLNRKDM4EGAA | |
| SCHEMBL8866132 | 0.78 | CTSA (0.45) | MAPTCYP1A2CTSAALDH1A1APLNR | |
| SCHEMBL25465653 | 0.78 | PTGER1 (0.46) | MAPTCYP1A2HPGDSALDH1A1GABRP | |
| SCHEMBL13755312 | 0.78 | CYP1A2 (0.43) | MAPTCYP1A2HPGDSALDH1A1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740574-A2 | 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES | Otsuka Pharmaceutical Company, Limited (JP) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105778-A2 | 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-11-10 | — | — | WO | disclosed |