Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PER2 | O15055 | 3/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3911411 | 0.80 | ACE (0.39) | PIK3CDACEPTPN1RAB9AALDH1A1 | |
| SCHEMBL3147824 | 0.77 | FKBP1A (0.40) | PIK3CDACEPTPN1ALDH1A1 | |
| SCHEMBL23328819 | 0.77 | PIK3CD (0.65) | PIK3CDPOLBHDAC1PER2CRY2 | |
| SCHEMBL24256488 | 0.74 | PIK3CD (0.67) | PIK3CDPOLBHDAC1PER2CRY2 | |
| SCHEMBL19701910 | 0.74 | PIK3CD (1.00) | PIK3CDPOLBPER2CRY2 | |
| SCHEMBL23469785 | 0.74 | PIK3CD (0.61) | PIK3CDPOLBHDAC1PER2CRY2 | |
| SCHEMBL27151784 | 0.74 | PIK3CD (0.61) | PIK3CDPOLBACEHDAC1PER2 | |
| SCHEMBL18664137 | 0.73 | PIK3CD (0.65) | PIK3CDPOLBPER2CRY2 | |
| SCHEMBL7506934 | 0.73 | PIK3CD (0.65) | PIK3CDPOLBACEHDAC1PER2 | |
| SCHEMBL18664136 | 0.73 | PIK3CD (0.65) | PIK3CDPOLBPER2CRY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831154-A2 | PREPARATION OF PREGABALIN AND RELATED COMPOUNDS | Warner-Lambert Company LLC (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006000904-A2 | PREPARATION OF PREGABALIN AND RELATED COMPOUNDS | WARNER-LAMBERT COMPANY LLC (US) | 2006-01-05 | — | — | WO | disclosed |