Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.32 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.32 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.32 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL6000976 | 0.86 | ALDH1A1 (0.38) | CYP3A4TDP1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL5504715 | 0.83 | CYP3A4 (0.30) | CYP3A4TDP1 | |
| SCHEMBL5506021 | 0.83 | DYRK1A (0.35) | CYP3A4TDP1MAPT | |
| SCHEMBL5502060 | 0.83 | CYP3A4 (0.30) | CYP3A4TDP1 | |
| SCHEMBL5505885 | 0.83 | DYRK1A (0.35) | CYP3A4TDP1MAPT | |
| SCHEMBL5506839 | 0.80 | HSD17B10 (0.39) | CYP3A4TDP1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL10336475 | 0.74 | TDP1 (0.51) | CYP3A4TDP1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL5224200 | 0.74 | KDM4E (0.39) | CYP3A4TDP1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL5505427 | 0.74 | PIK3CD (0.35) | ALDH1A1 | |
| SCHEMBL5501897 | 0.74 | TLR8 (0.47) | TDP1ALDH1A1TSHRHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846108-A2 | KERATIN DYEING COMPOSITIONS CONTAINING BENZOTHIAZOLE-4,7-DIAMINES, AND USE THEREOF | The Procter & Gamble Company (US) | 2007-10-24 | — | — | EP | claimed |
| WO-2006078800-A2 | KERATIN DYEING COMPOSITIONS CONTAINING BENZOTHIAZOLE-4-, 7-DIAMINES, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-27 | — | — | WO | claimed |
| US-20060162099-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2006-07-27 | — | — | US | claimed |
| EP-1846108-A2 | KERATIN DYEING COMPOSITIONS CONTAINING BENZOTHIAZOLE-4,7-DIAMINES, AND USE THEREOF | The Procter & Gamble Company (US) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006078800-A2 | KERATIN DYEING COMPOSITIONS CONTAINING BENZOTHIAZOLE-4-, 7-DIAMINES, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-27 | — | — | WO | disclosed |
| US-20060162099-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060162099-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, DSP, KRTCAP2 | CYP3A4 912/4885TDP1 2779/4885ALDH1A1 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.