Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | PGK2 | P07205 | 1/20 | 0.39 |
| ▸ | PGD | P52209 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.35 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.35 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9285761 | 0.86 | CA1 (0.53) | CA1CA2CA7LPAR5MPI | |
| SCHEMBL4563781 | 0.86 | CA1 (0.53) | CA1CA2CA7LPAR5MPI | |
| SCHEMBL585036 | 0.86 | CA1 (0.53) | CA1CA2CA7LPAR5MPI | |
| SCHEMBL28051142 | 0.85 | MPI (0.38) | CA1CA2CA7LPAR5MPI | |
| Phosphoric Acid SCHEMBL30509812 | 0.84 | CA1 (0.52) | CA1CA2CA7LPAR5MPI | |
| SCHEMBL27973226 | 0.84 | CA1 (0.52) | CA1CA2CA7LPAR5MPI | |
| Phosphoric Acid SCHEMBL170152 | 0.84 | CA1 (0.55) | CA1CA2CA7LPAR5SMN1; SMN2 | |
| SCHEMBL7341 | 0.83 | PGK1 (0.52) | LPAR5MPIPGK1PGK2PGD | |
| SCHEMBL14278848 | 0.83 | PGK1 (0.52) | LPAR5MPIPGK1PGK2PGD | |
| SCHEMBL213379 | 0.83 | PGK1 (0.52) | LPAR5MPIPGK1PGK2PGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613298-A4 | LYSOPHOSPHATIDIC ACID ANALOGS AND INHIBITION OF NEOINTIMA FORMATION | UNIV TENNESSEE RES FOUNDATION (US) | 2007-10-03 | — | — | EP | claimed |
| EP-1613298-A2 | LYSOPHOSPHATIDIC ACID ANALOGS AND INHIBITION OF NEOINTIMA FORMATION | The University of Tennessee Research Foundation (US) | 2006-01-11 | — | — | EP | claimed |
| WO-2004091496-A2 | LYSOPHOSPHATIDIC ACID ANALOGS AND INHIBITION OF NEOINTIMA FORMATION | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2004-10-28 | — | — | WO | claimed |
| US-20040204383-A1 | Lysophosphatidic acid analogs and inhibition of neointima formation | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE | 2004-10-14 | — | — | US | claimed |
| EP-1613298-A4 | LYSOPHOSPHATIDIC ACID ANALOGS AND INHIBITION OF NEOINTIMA FORMATION | UNIV TENNESSEE RES FOUNDATION (US) | 2007-10-03 | — | — | EP | disclosed |
| EP-1613298-A2 | LYSOPHOSPHATIDIC ACID ANALOGS AND INHIBITION OF NEOINTIMA FORMATION | The University of Tennessee Research Foundation (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004091496-A2 | LYSOPHOSPHATIDIC ACID ANALOGS AND INHIBITION OF NEOINTIMA FORMATION | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2004-10-28 | — | — | WO | disclosed |
| US-20040204383-A1 | Lysophosphatidic acid analogs and inhibition of neointima formation | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE | 2004-10-14 | — | — | US | disclosed |