SCHEMBL5501259

SCHEMBL5501259

O=C(O)c1cccc(I)c1OI.[LiH]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
KDM4E B2RXH2 4/20 0.43
HPGD P15428 3/20 0.43
HSD17B10 Q99714 3/20 0.43
MAPK1 P28482 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.38
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38
NR4A3 Q92570 1/20 0.38
KEAP1 Q14145 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NAPRT Q6XQN6 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
HMGB1 P09429 1/20 0.38
CA4 P22748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL606645 0.98 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDHSD17B10MAPK1
Lithium SCHEMBL5501261 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL16415833 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL9482456 0.96 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDHSD17B10MAPK1
Boric Acid SCHEMBL28709329 0.95 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDHSD17B10MAPK1
Bicarbonate SCHEMBL5507507 0.91 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDHSD17B10MAPK1
Lithium Ion SCHEMBL28610344 0.88 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL28715668 0.83 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL31050144 0.81 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL1708884 0.81 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDHSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090042-A1 SINGLE-CELL AND SPATIAL DNA METHYLATION MEASUREMENTS THE BROAD INSTITUTE, INC. (US) 2026-04-30 WO disclosed
US-20240376460-A1 HIGH-THROUGHPUT SINGLE-CELL SEQUENCING WITH REDUCED AMPLIFICATION BIAS ILLUMINA, INC. 2024-11-14 US disclosed
US-11981891-B2 High-throughput single-cell sequencing with reduced amplification bias ILLUMINA, INC. (US) 2024-05-14 US disclosed
US-20230323426-A1 SINGLE CELL WHOLE GENOME LIBRARIES AND COMBINATORIAL INDEXING METHODS OF MAKING THEREOF ILLUMINA INC. (US) 2023-10-12 US disclosed
US-11535883-B2 Single cell whole genome libraries and combinatorial indexing methods of making thereof ILLUMINA, INC. (US) 2022-12-27 US disclosed
CN-109809961-A Iodine-containing photoacid generators and compositions comprising same 罗门哈斯电子材料有限责任公司 2019-05-28 CN disclosed
CN-101918212-B There is the transparent multilayer sheet of electrostatic dissipative properties LUBRIZOL ADVANCED MATERIALS, INC. (US) 2016-04-27 CN disclosed
CN-101918212-A Transparent multilayer sheet having electrostatic dissipative properties LUBRIZOL ADVANCED MAT INC 2010-12-15 CN disclosed
EP-1673105-B1 USE OF FOLLICLE STIMULATING HORMONE FOR REDUCTION OF SPERMATOZOA CHROMOSOMAL ABERRATION IN MALES SERONO LAB (CH) 2007-05-02 EP disclosed
US-20070037742-A1 Use of follicle stimulating hormone for reduction of spermatozoa chromosomal aberration in males LABORATORIES SERONO S.A. (CH) 2007-02-15 US disclosed
EP-1673105-A1 USE OF FOLLICLE STIMULATING HORMONE FOR REDUCTION OF SPERMATOZOA CHROMOSOMAL ABERRATION IN MALES LABORATOIRES SERONO S.A. (CH) 2006-06-28 EP disclosed
WO-2005011726-A1 USE OF FOLLICLE STIMULATING HORMONE FOR REDUCTION OF SPERMATOZOA CHROMOSOMAL ABERRATION IN MALES LABORATOIRES SERONO S.A. (CH) 2005-02-10 WO disclosed
CN-1127570-C Application of castor silkworm cell nucleus and skeleton combination elements SHANGHAI INST OF BIOLOG CHEMIS (CN) 2003-11-12 CN disclosed
US-20020073448-A1 Matrix attachment regions NATIONAL SCIENCE FOUNDATION 2002-06-13 US disclosed
EP-1005560-A1 MATRIX ATTACHMENT REGIONS NORTH CAROLINA STATE UNIVERSITY (US) 2000-06-07 EP disclosed
CN-1223299-A Application of castor silkworm cell nucleus and skeleton combination elements SHANGHAI INST OF BIOLOG CHEMIS (CN) 1999-07-21 CN disclosed
WO-1999007866-A1 MATRIX ATTACHMENT REGIONS NORTH CAROLINA STATE UNIVERSITY (US) 1999-02-18 WO disclosed
US-4906571-A Cell surface modification using a novel glycoproteinase of pasteurella haemolytica UNIVERSITY OF GUELPH (CA) 1990-03-06 US disclosed