SCHEMBL606645

SCHEMBL606645

O=C(O)c1cccc(I)c1OI

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
KDM4E B2RXH2 4/20 0.44
HPGD P15428 3/20 0.44
HSD17B10 Q99714 3/20 0.44
ALOX15 P16050 1/20 0.44
MAPK1 P28482 1/20 0.44
TSHR P16473 1/20 0.39
NR4A1 P22736 1/20 0.39
NR4A2 P43354 1/20 0.39
NR4A3 Q92570 1/20 0.39
KEAP1 Q14145 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NAPRT Q6XQN6 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
HMGB1 P09429 1/20 0.39
CA4 P22748 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lithium SCHEMBL5501261 0.98 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDHSD17B10ALOX15
SCHEMBL5501259 0.98 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDHSD17B10ALOX15
SCHEMBL16415833 0.98 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDHSD17B10ALOX15
SCHEMBL9482456 0.98 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDHSD17B10ALOX15
Boric Acid SCHEMBL28709329 0.93 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDHSD17B10ALOX15
Bicarbonate SCHEMBL5507507 0.93 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDHSD17B10ALOX15
Lithium Ion SCHEMBL28610344 0.90 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDHSD17B10ALOX15
SCHEMBL28715668 0.84 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDHSD17B10ALOX15
SCHEMBL30410033 0.82 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDHSD17B10ALOX15
SCHEMBL31050144 0.82 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3981884-B1 SINGLE CELL WHOLE GENOME LIBRARIES FOR METHYLATION SEQUENCING UNIV OREGON HEALTH & SCIENCE (US) 2023-08-09 EP claimed
EP-3635136-B1 SINGLE CELL WHOLE GENOME LIBRARIES FOR METHYLATION SEQUENCING UNIV OREGON HEALTH & SCIENCE (US) 2021-10-20 EP claimed
US-20160166507-A1 NANOEMULSIONS OF HYDROPHOBIC PLATINUM DERIVATIVES Nemucore Medical Innovations, Inc. (US) 2016-06-16 US claimed
CN-104749887-A COMPOSITION FOR FORMING RESIST UNDERLAYER FILM FOR EUV LITHOGRAPHY NISSAN CHEMICAL IND LTD 2015-07-01 CN claimed
US-9005873-B2 Composition for forming resist underlayer film for EUV lithography NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-04-14 US claimed
CN-103787876-A Synthesis method of medical intermediate 3,5-diiodosalicylic acid JIANGSU HAOHUA FINE CHEMICAL CO LTD 2014-05-14 CN claimed
CN-103755556-A Chemical synthesis method for 3,5-diiodosalicylic acid HONG ZHI 2014-04-30 CN claimed
US-20140099791-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM FOR EUV LITHOGRAPHY NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-04-10 US claimed
CN-102422985-B Iodine, selenium and cobalt composite package for animal feed and preparation method and application method thereof CHANGSHA XINGJIA BIOLOG TECHNOLOGY CO LTD 2013-03-20 CN claimed
CN-102422985-A Iodine selenium cobalt composite bag for animal feed and preparation method and application method thereof CHANGSHA XINGJIA BIOLOG TECHNOLOGY CO LTD 2012-04-25 CN claimed
CN-102414619-A Resist underlayer film forming composition for EUV lithography NISSAN CHEMICAL IND LTD 2012-04-11 CN claimed
US-20120040291-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM FOR EUV LITHOGRAPHY NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-02-16 US claimed
CN-1923837-A Lipophilic platinum antineoplastic complex KUNMING GUIYAN PHARMACEUTICAL (CN) 2007-03-07 CN claimed
CN-1330679-A Plastic moulding materials which can be detected by x-ray contrast BAYER AG (DE) 2002-01-09 CN claimed
EP-0246978-B1 REAGENT FOR RENDERING BIOLOGICAL FLUIDS TRANSPARENT AND ITS ANALYTICAL APPLICATIONS UNIVERSITE DE NANCY I (FR) 1991-01-09 EP claimed
EP-0285025-A2 Silylated poly(vinyl)phenol resists SHIPLEY COMPANY INC. (US) 1988-10-05 EP claimed
EP-0246978-A1 Reagent for rendering biological fluids transparent and its analytical applications UNIVERSITE DE NANCY I (FR) 1987-11-25 EP claimed
JP-6237798-A None JP disclosed
US-4410541-A MONOIODOHIST DINE, FEEDING IODINE COMPOUNDS TO EGG LAYING BIRDS NIHON NOSAN KOGYO K.K. (JP) 1983-10-18 US disclosed
US-4394376-A IODINE-ENRICHED EGGS NIHON NOSAN KOGYO K.K. (JP) 1983-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160166507-A1 NANOEMULSIONS OF HYDROPHOBIC PLATINUM DERIVATIVES MCL1, TUBA3E, HSPE1 ALDH1A1 2369/4885KDM4E 4548/4885HPGD 425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.