Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | ADH1B | P00325 | 1/20 | 0.45 |
| ▸ | ADH1C | P00326 | 1/20 | 0.45 |
| ▸ | ADH1A | P07327 | 1/20 | 0.45 |
| ▸ | ADH7 | P40394 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5385718 | 0.98 | MEN1 (0.54) | MEN1KMT2ATDP1MAOAMAPT | |
| SCHEMBL15114181 | 0.83 | MEN1 (0.58) | MEN1KMT2ATDP1MAOAMAPT | |
| SCHEMBL3376434 | 0.81 | MEN1 (0.51) | MEN1KMT2ATDP1MAOAMAPT | |
| SCHEMBL22039743 | 0.80 | CYP3A4 (0.61) | MEN1KMT2ACHRM2CYP3A4KDM4E | |
| SCHEMBL23190504 | 0.79 | MEN1 (0.48) | MEN1KMT2ATDP1MAOAMAPT | |
| SCHEMBL15114173 | 0.79 | MEN1 (0.49) | MEN1KMT2ATDP1MAOAMAPT | |
| SCHEMBL17700160 | 0.79 | MEN1 (0.48) | MEN1KMT2ATDP1MAOAMAPT | |
| SCHEMBL21635232 | 0.78 | MEN1 (0.64) | MEN1KMT2ATDP1MAOAMAPT | |
| SCHEMBL549085 | 0.78 | SIGMAR1 (0.55) | MAOAMAPTGAASIGMAR1IDO1 | |
| Hydrochloric Acid SCHEMBL5378426 | 0.78 | CYP3A4 (0.59) | MEN1KMT2ACHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1263514-C | Fluoro labelled anthracyclinone and anthracycline derivatives | PHARMACIA & UPJOHN SPA (IT) | 2006-07-12 | — | — | CN | claimed |
| CN-1223592-A | 19F-labelled anthracyclinones and anthracycline derivatives | PHARMACIA & UPJOHN SPA (IT) | 1999-07-21 | — | — | CN | claimed |
| EP-3770148-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2021-01-27 | — | — | EP | disclosed |
| WO-2020147848-A1 | TRICYCLIC SUBSTITUTED OXASPIRO DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 上海海雁医药科技有限公司 | 2020-07-23 | — | — | WO | disclosed |
| WO-2019016385-A1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2019-01-24 | — | — | WO | disclosed |
| EP-2225223-B1 | ORGANIC COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2017-01-11 | — | — | EP | disclosed |
| EP-2225227-B1 | 1',3'-Dihydrospiro[imidazolidin-4,2'-inden]-2,5-diones and 1,3-dihydrospiro[inden-2,3']-pyrroles as CGRP antagonists | BOEHRINGER INGELHEIM INT (DE) | 2015-08-26 | — | — | EP | disclosed |
| EP-2225227-B1 | 1',3'-Dihydrospiro[imidazolidin-4,2'-inden]-2,5-diones and 1,3-dihydrospiro[inden-2,3']-pyrroles as CGRP antagonists | BOEHRINGER INGELHEIM INT (DE) | 2015-08-26 | — | — | EP | disclosed |
| US-8829006-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-09 | — | — | US | disclosed |
| US-8110575-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-07 | — | — | US | disclosed |
| US-8110575-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-07 | — | — | US | disclosed |
| WO-2009065920-A2 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009065920-A2 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-28 | — | — | WO | disclosed |
| EP-2062889-A1 | Compounds | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2009-05-27 | — | — | EP | disclosed |
| WO-2009029998-A1 | RETROMETABOLIC COMPOUNDS | CYTOPIA RESEARCH PTY LTD (AU) | 2009-03-12 | — | — | WO | disclosed |
| CN-1263514-C | Fluoro labelled anthracyclinone and anthracycline derivatives | PHARMACIA & UPJOHN SPA (IT) | 2006-07-12 | — | — | CN | disclosed |
| CN-1499972-A | Imidazolyl derivatives as corticotropin releasing factor inhibitors | ����˹�ж�-����˹˹������˾ | 2004-05-26 | — | — | CN | disclosed |
| EP-0910415-B1 | FLUORO-LABELLED ANTHRACYCLINE AND ANTHRACYCLINONE DERIVATIVES | PHARMACIA ITALIA SPA (IT) | 2004-05-12 | — | — | EP | disclosed |
| US-6103700-A | FOR DIAGNOSING AMYLOIDOSIS | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-08-15 | — | — | US | disclosed |
| CN-1223592-A | 19F-labelled anthracyclinones and anthracycline derivatives | PHARMACIA & UPJOHN SPA (IT) | 1999-07-21 | — | — | CN | disclosed |