Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5378426 | 0.98 | CYP3A4 (0.59) | CYP3A4CYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL1796909 | 0.81 | LMNA (0.77) | CYP3A4CYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL184001 | 0.81 | LMNA (0.77) | CYP3A4CYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL6566557 | 0.81 | SMN1; SMN2 (0.59) | CYP3A4CYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL3606710 | 0.81 | PYCR1 (0.50) | CYP3A4CYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL23075813 | 0.81 | CYP3A4 (0.59) | CYP3A4CYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL17953203 | 0.81 | KMT2A (0.56) | CYP3A4CYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL2581883 | 0.81 | LOXL2 (0.43) | CYP3A4CYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL550153 | 0.80 | MEN1 (0.56) | CYP3A4CHRM2KMT2AMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL5381334 | 0.79 | SMN1; SMN2 (0.57) | LMNACHRM2KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020108500-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | 成都海创药业有限公司 | 2020-06-04 | — | — | WO | disclosed |