Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31095607 | 1.00 | MAPT (0.50) | MAPTTSHRGLAPOLBGAA | |
| SCHEMBL5495682 | 1.00 | MAPT (0.50) | MAPTTSHRGLAPOLBGAA | |
| SCHEMBL4970196 | 0.89 | TSHR (0.46) | MAPTTSHRGLAPOLBGAA | |
| SCHEMBL27970953 | 0.79 | FFAR1 (0.55) | MAPTTSHRGLAPOLBGAA | |
| SCHEMBL3275176 | 0.78 | MAPT (0.61) | MAPTNPC1KDM4EMEN1ALDH1A1 | |
| SCHEMBL563999 | 0.78 | FFAR1 (0.60) | MAPTTSHRNPC1KDM4EMEN1 | |
| SCHEMBL7531908 | 0.77 | MAPT (0.59) | MAPTTSHRPOLBNPC1KDM4E | |
| SCHEMBL6865700 | 0.76 | FFAR1 (0.49) | NPC1FFAR1PTPN1HAO1RAB9A | |
| SCHEMBL31095611 | 0.74 | CASP3 (0.48) | MAPTPOLBNPC1MEN1ALDH1A1 | |
| SCHEMBL15544149 | 0.74 | MAPT (0.55) | MAPTTSHRGAANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118652429-A | Fluorine-containing phenylacetylene aniline end-capped high heat-resistant polyether sulfone resin and preparation method thereof | 濮阳市盛通聚源新材料有限公司 | 2024-09-17 | — | — | CN | claimed |
| CN-116666894-A | Heat-resistant composite diaphragm and preparation method thereof | 天能电池集团股份有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-118652429-A | Fluorine-containing phenylacetylene aniline end-capped high heat-resistant polyether sulfone resin and preparation method thereof | 濮阳市盛通聚源新材料有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-116666894-A | Heat-resistant composite diaphragm and preparation method thereof | 天能电池集团股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-1836174-B2 | ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS | AMGEN INC (US) | 2019-10-02 | — | — | EP | disclosed |
| EP-1836174-B1 | ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS | AMGEN INC (US) | 2013-02-27 | — | — | EP | disclosed |
| US-20070054916-A1 | Aryl nitrogen-containing bicyclic compounds and methods of use | AMGEN INC. | 2007-03-08 | — | — | US | disclosed |
| US-20070054916-A1 | Aryl nitrogen-containing bicyclic compounds and methods of use | AMGEN INC. | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054916-A1 | Aryl nitrogen-containing bicyclic compounds and methods of use | MAP3K1, MAP3K5, MAP3K2 | MAPT 4333/4885TSHR 2958/4885GLA 3988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.