Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 12/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502896 | 0.90 | F10 (0.36) | F10GRM2GRIA1CACNG8 | |
| SCHEMBL5499028 | 0.88 | F10 (0.37) | F10GRM2GRIA1CACNG8 | |
| SCHEMBL5502616 | 0.85 | F10 (0.35) | F10 | |
| SCHEMBL5499874 | 0.83 | F10 (0.39) | F10GRM2GRIA1CACNG8 | |
| SCHEMBL5502999 | 0.80 | F10 (0.37) | F10GRIA1CACNG8 | |
| SCHEMBL5502470 | 0.80 | F10 (0.37) | F10GRIA1CACNG8 | |
| SCHEMBL4659280 | 0.79 | F10 (0.36) | F10GRM2GRIA1CACNG8 | |
| SCHEMBL5504321 | 0.73 | GRIA1 (0.39) | GRIA1CACNG8 | |
| SCHEMBL5499076 | 0.72 | GRM2 (0.37) | F10GRM2 | |
| SCHEMBL5506392 | 0.71 | GRM2 (0.36) | F10GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869029-A1 | AN OXINDOLE OXAZOLIDINONE AS ANTIBACTERIAL AGENT | Pharmacia & Upjohn Company LLC (US) | 2007-12-26 | — | — | EP | disclosed |
| EP-1781643-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006106426-A1 | AN OXINDOLE OXAZOLIDINONE AS ANTIBACTERIAL AGENT | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-10-12 | — | — | WO | disclosed |
| WO-2006016220-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |