SCHEMBL5506392

SCHEMBL5506392

CC(C)c1c(N2C[C@@H](CN)OC2=O)cc2c(c1F)NC(=O)C2

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 8/20 0.36
F10 P00742 1/20 0.35
MAOB P27338 1/20 0.31
CALML3 P27482 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5499076 0.87 GRM2 (0.37) GRM2F10MAOBCALML3
SCHEMBL5500465 0.83 F10 (0.35) GRM2F10
SCHEMBL5502203 0.81 F10 (0.34) GRM2F10
SCHEMBL4659280 0.76 F10 (0.36) GRM2F10
SCHEMBL5502292 0.74 AHR (0.32)
SCHEMBL5499874 0.73 F10 (0.39) GRM2F10MAOB
SCHEMBL5502896 0.72 F10 (0.36) GRM2F10CALML3
SCHEMBL5499028 0.71 F10 (0.37) GRM2F10
SCHEMBL5501644 0.71 F10 (0.35) GRM2F10
SCHEMBL5502470 0.70 F10 (0.37) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1869030-A1 7-FLUORO-1,3-DIHYDRO-INDOL-2-ONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS Pharmacia & Upjohn Company LLC (US) 2007-12-26 EP disclosed
WO-2006106427-A1 7-FLUORO-1,3-DIHYDRO-INDOL-2-ONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2006-10-12 WO disclosed