Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 5/20 | 0.43 |
| ▸ | GRM7 | Q14831 | 5/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27732356 | 0.82 | GRM8 (0.47) | GRM8GRM7GRM1GRM4GRM5 | |
| SCHEMBL21436988 | 0.81 | GRM8 (0.51) | GRM8GRM7GRM1GRM4GRM5 | |
| SCHEMBL6125509 | 0.79 | KMT2A (0.51) | GRM8GRM7GRM1GRM4GRM5 | |
| SCHEMBL5502020 | 0.78 | HTR5A (0.37) | — | |
| SCHEMBL5495275 | 0.77 | KMT2A (0.44) | KMT2AMEN1USP2MAPTTSHR | |
| SCHEMBL14152995 | 0.76 | GRM8 (0.43) | GRM8GRM7GRM1GRM4GRM5 | |
| SCHEMBL28633848 | 0.74 | KMT2A (0.50) | GRM8GRM7GRM1GRM4GRM5 | |
| SCHEMBL5500670 | 0.74 | MEN1 (0.41) | GRM8GRM7KMT2AMEN1USP2 | |
| SCHEMBL5501387 | 0.73 | MEN1 (0.40) | KMT2AMEN1USP2MAPTTSHR | |
| SCHEMBL3894831 | 0.72 | CYP3A4 (0.38) | GRM8GRM7GRM1GRM4GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765592-A1 | METHOD FOR MAKING NEGATIVE-WORKING HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR | Agfa Graphics N.V. (BE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005688-A1 | METHOD FOR MAKING NEGATIVE-WORKING HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR. | AGFA-GEVAERT (BE) | 2006-01-19 | — | — | WO | disclosed |