Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5496349 | 0.89 | HTR5A (0.38) | HTR5AEGFRDRD2SLC6A2HTR2A | |
| SCHEMBL5501909 | 0.78 | GRM8 (0.43) | — | |
| SCHEMBL5501013 | 0.77 | HTR5A (0.36) | HTR5AHTR2AHTR2CHTR7DDB1 | |
| SCHEMBL27589412 | 0.74 | HTR5A (0.35) | HTR5ADDB1CRBN | |
| SCHEMBL10851169 | 0.73 | IDO1 (0.62) | DRD2HTR2AHTR2CHTR7 | |
| SCHEMBL3892963 | 0.72 | ALDH1A1 (0.40) | — | |
| SCHEMBL5814656 | 0.71 | IDO1 (0.64) | DRD2HTR2AHTR2CHTR7 | |
| SCHEMBL24631309 | 0.68 | HTR5A (0.53) | HTR5AEGFR | |
| SCHEMBL16264954 | 0.66 | IDO1 (0.66) | DRD2HTR2AHTR2CHTR7 | |
| SCHEMBL167383 | 0.65 | LIPG (0.44) | DRD2SLC6A2HTR2AHTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765592-A1 | METHOD FOR MAKING NEGATIVE-WORKING HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR | Agfa Graphics N.V. (BE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005688-A1 | METHOD FOR MAKING NEGATIVE-WORKING HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR. | AGFA-GEVAERT (BE) | 2006-01-19 | — | — | WO | disclosed |