Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.75 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.75 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.75 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.61 |
| ▸ | RRM1 | P23921 | 1/20 | 0.59 |
| ▸ | GSR | P00390 | 1/20 | 0.55 |
| ▸ | TERT | O14746 | 5/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | NOS1 | P29475 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12829586 | 1.00 | GNAI3 (0.75) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL5497787 | 0.98 | GNAI3 (0.73) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL5501940 | 0.96 | GNAI3 (0.75) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL5497912 | 0.94 | GNAI3 (0.69) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL31633172 | 0.94 | GNAI3 (0.84) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL18851288 | 0.94 | GNAI3 (0.84) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL14153187 | 0.94 | GNAI3 (0.84) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL18851611 | 0.94 | GNAI3 (0.84) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL31633196 | 0.94 | GNAI3 (0.84) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL5499939 | 0.94 | GNAI3 (0.72) | GNAI3GNAO1GNAI1DPP7RRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100816-B1 | AEROTHRICIN ANALOGS, THEIR PREPARATION AND USE | BASILEA PHARMACEUTICA AG (CH) | 2007-08-08 | — | — | EP | disclosed |
| EP-1251827-B1 | NASALLY ADMINISTRABLE ANTIFUNGAL CYCLIC PEPTIDE COMPOSITIONS | BASILEA PHARMACEUTICA AG (CH) | 2004-05-26 | — | — | EP | disclosed |
| US-6489440-B1 | Cyclic compounds | BASILEA PHARMACEUTICA AG (CH) | 2002-12-03 | — | — | US | disclosed |
| EP-1251827-A2 | NASALLY ADMINISTRABLE CYCLIC PEPTIDE COMPOSITIONS | Basilea Pharmaceutica AG (CH) | 2002-10-30 | — | — | EP | disclosed |
| US-20010038824-A1 | Intranasal cyclic peptide formulations | BASILEA PHARMACEUTICA AG (CH) | 2001-11-08 | — | — | US | disclosed |
| WO-2001052894-A2 | NASALLY ADMINISTRABLE CYCLIC PEPTIDE COMPOSITIONS | BASILEA PHARMACEUTICA AG (CH) | 2001-07-26 | — | — | WO | disclosed |
| EP-1100816-A1 | AEROTHRICIN ANALOGS, THEIR PREPARATION AND USE | F. HOFFMANN-LA ROCHE AG (CH) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000005251-A1 | AEROTHRICIN ANALOGS, THEIR PREPARATION AND USE | F. HOFFMANN-LA ROCHE AG (CH) | 2000-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010038824-A1 | Intranasal cyclic peptide formulations | VIP, NPPA, SSTR5 | GNAI3 3398/4885GNAO1 3347/4885GNAI1 2883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.