SCHEMBL5502197

SCHEMBL5502197

COc1cc(OC)nc(CCSC)n1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PDE2A O00408 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
CYP1A2 P05177 1/20 0.35
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
RECQL P46063 1/20 0.33
ADORA3 P0DMS8 2/20 0.32
POLB P06746 1/20 0.32
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
ADORA1 P30542 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2887498 0.79 LMNA (0.41) LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2
SCHEMBL13069321 0.77 SMN1; SMN2 (0.42) LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2
SCHEMBL5502085 0.75 LMNA (0.41) LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2
SCHEMBL12479632 0.72 TNKS2 (0.41) LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2
SCHEMBL8343522 0.72 LMNA (0.45) LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2
SCHEMBL15752122 0.70 LMNA (0.48) LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2
SCHEMBL13983020 0.70 TDP1 (0.44) LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2
SCHEMBL4595225 0.70 LMNA (0.43) LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2
SCHEMBL10048775 0.70 LMNA (0.43) LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2
SCHEMBL13738921 0.70 CYP1A2 (0.44) LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1773124-A1 A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE Bayer CropScience Aktiengesellschaft (DE) 2007-04-18 EP disclosed
WO-2006008159-A1 A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE BAYER CROPSCIENCE AG (DE) 2006-01-26 WO disclosed