Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 3/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502197 | 0.79 | LMNA (0.38) | LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2 | |
| SCHEMBL8343522 | 0.75 | LMNA (0.45) | LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2 | |
| SCHEMBL15752122 | 0.73 | LMNA (0.48) | LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2 | |
| SCHEMBL13983020 | 0.73 | TDP1 (0.44) | LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2 | |
| SCHEMBL379405 | 0.73 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2 | |
| SCHEMBL4918384 | 0.73 | LOXL2 (0.44) | LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2 | |
| SCHEMBL4595225 | 0.73 | LMNA (0.43) | LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2 | |
| SCHEMBL10048775 | 0.73 | LMNA (0.43) | LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2 | |
| SCHEMBL13738921 | 0.73 | CYP1A2 (0.44) | LMNASMN1; SMN2PDE2AL3MBTL1CYP1A2 | |
| SCHEMBL3784384 | 0.73 | NOS3 (0.33) | NOS3NOS1NOS2CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096551-B2 | Method for producing 2-(triazinylcarbonyl) sulfonanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| CN-102633729-B | A use of sulfonanilides as herbicide | BAYER CROPSCIENCE AG | 2015-06-03 | — | — | CN | disclosed |
| EP-2655346-B1 | PROCESS FOR THE PREPARATION OF 2-(TRIAZINYLCARBONYL)SULFONANILIDES | BAYER IP GMBH (DE) | 2015-01-21 | — | — | EP | disclosed |
| US-20140024828-A1 | Method for producing 2-(triazinylcarbonyl) sulfonanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-23 | — | — | US | disclosed |
| WO-2012084857-A2 | METHOD FOR PRODUCING 2-(TRIAZINYLCARBONYL) SULFONANILIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | WO | disclosed |
| US-20100323896-A1 | USE OF SULFONANILIDES AS HERBICIDE | BAYER CROPSCIENCE AG (DE) | 2010-12-23 | — | — | US | disclosed |
| US-7829703-B2 | Difluoromethanesulfonyl anilide derivatives useful as herbicides | BAYER CROPSCIENCE AG (DE) | 2010-11-09 | — | — | US | disclosed |
| CN-101848641-A | Sulfonanilide compounds is as the purposes of weed killer herbicide | BAYER CROPSCIENCE AG | 2010-09-29 | — | — | CN | disclosed |
| US-7772395-B2 | Process for the preparation of phenyl 2-pyrimidinyl ketones and their novel intermediates | BAYER CROPSCIENCE AG (DE) | 2010-08-10 | — | — | US | disclosed |
| EP-1807401-B1 | PROCESS FOR THE PREPARATION OF PHENYL 2-PYRIMIDINYL KETONES AND THEIR NOVEL INTERMEDIATES | BAYER CROPSCIENCE AG (DE) | 2010-07-07 | — | — | EP | disclosed |
| EP-1928242-A2 | A USE OF SULFONANILIDES AS HERBICIDE | Bayer CropScience AG (DE) | 2008-06-11 | — | — | EP | disclosed |
| US-20080004444-A1 | Process for the Preparation of Phenyl 2-Pyrimidinyl Ketones and Their Novel Intermediates | BAYER CORPSCIENCE AG (DE) | 2008-01-03 | — | — | US | disclosed |
| US-20070197390-A1 | Difluoromethanesulfonyl anilide derivatives useful as herbicides | BAYER CROPSCIENCE AG (DE) | 2007-08-23 | — | — | US | disclosed |
| EP-1750510-B1 | DIFLUOROMETHANESULFONYL ANILIDE DERIVATIVES USEFUL AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2007-08-22 | — | — | EP | disclosed |
| EP-1807401-A1 | PROCESS FOR THE PREPARATION OF PHENYL 2-PYRIMIDINYL KETONES AND THEIR NOVEL INTERMEDIATES | Bayer CropScience AG (DE) | 2007-07-18 | — | — | EP | disclosed |
| WO-2007031208-A2 | A USE OF SULFONANILIDES AS HERBICIDE | BAYER CROPSCIENCE AG (DE) | 2007-03-22 | — | — | WO | disclosed |
| EP-1750510-A1 | DIFLUOROMETHANESULFONYL ANILIDE DERIVATIVES USEFUL AS HERBICIDES | Bayer CropScience AG (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2006045612-A1 | PROCESS FOR THE PREPARATION OF PHENYL 2-PYRIMIDINYL KETONES AND THEIR NOVEL INTERMEDIATES | BAYER CROPSCIENCE AG (DE) | 2006-05-04 | — | — | WO | disclosed |
| WO-2005096818-A1 | DIFLUOROMETHANESULFONYL ANILIDE DERIVATIVES USEFUL AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2005-10-20 | — | — | WO | disclosed |
| WO-1996041799-A1 | SULPHONAMIDES AS HERBICIDES AND PLANT-GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1996-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024828-A1 | Method for producing 2-(triazinylcarbonyl) sulfonanilides | AOX1, SULT1E1, CBR1 | LMNA 3282/4885SMN1; SMN2 2787/4885PDE2A 2839/4885 |
| US-20100323896-A1 | USE OF SULFONANILIDES AS HERBICIDE | CBR3, HCAR3, HCRTR1 | LMNA 4414/4885SMN1; SMN2 3502/4885PDE2A 4401/4885 |
| US-20070197390-A1 | Difluoromethanesulfonyl anilide derivatives useful as herbicides | PFAS, DDT, HDHD5 | LMNA 4641/4885SMN1; SMN2 4427/4885PDE2A 1758/4885 |
| US-20080004444-A1 | Process for the Preparation of Phenyl 2-Pyrimidinyl Ketones and Their Novel Intermediates | PDK2, PDK4, PDK1 | LMNA 3165/4885SMN1; SMN2 1958/4885PDE2A 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.