SCHEMBL5502383

SCHEMBL5502383

C=CCC(OP(=O)(O)O)C(O)CO

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.37
MPI P34949 1/20 0.32
LPAR2 Q9HBW0 1/20 0.31
LPAR3 Q9UBY5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15392358 1.00 PTPN1 (0.37) PTPN1MPILPAR2LPAR3
SCHEMBL6694351 1.00 PTPN1 (0.37) PTPN1MPILPAR2LPAR3
SCHEMBL139867 0.83 PTPN1 (0.38) PTPN1MPI
SCHEMBL6429913 0.83 PTPN1 (0.38) PTPN1MPI
SCHEMBL2216482 0.80 PTPN1 (0.43) PTPN1MPI
SCHEMBL28033517 0.80 PTPN1 (0.43) PTPN1MPI
SCHEMBL2859327 0.76 CA1 (0.37) PTPN1
SCHEMBL97667 0.76 LMNA (0.33)
SCHEMBL87985 0.75 CA1 (0.31)
SCHEMBL6470157 0.75 PTPN1 (0.47) PTPN1MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3442992-B1 METHODS FOR IDENTIFYING MODULATORS OF GPR92 MARS INC (US) 2024-04-10 EP claimed
US-20190170772-A1 METHODS FOR IDENTIFYING MODULATORS OF GPR92 MARS, INCORPORATED (US) 2019-06-06 US claimed
EP-3442992-B1 METHODS FOR IDENTIFYING MODULATORS OF GPR92 MARS INC (US) 2024-04-10 EP disclosed
US-11237177-B2 Methods for identifying modulators of GPR92 MARS, INCORPORATED (US) 2022-02-01 US disclosed
US-20210315244-A1 COMPOUNDS THAT MODULATE GPR92 RECEPTOR ACTIVITY AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2021-10-14 US disclosed
EP-3846640-A1 COMPOUNDS THAT MODULATE GPR92 RECEPTOR ACTIVITY AND PET FOOD PRODUCTS CONTAINING THE SAME Mars Incorporated (US) 2021-07-14 EP disclosed
US-20190170772-A1 METHODS FOR IDENTIFYING MODULATORS OF GPR92 MARS, INCORPORATED (US) 2019-06-06 US disclosed
EP-3442992-A1 METHODS FOR IDENTIFYING MODULATORS OF GPR92 Mars, Incorporated (US) 2019-02-20 EP disclosed
CN-109071608-A The method for identifying GPR92 regulator 马斯公司 2018-12-21 CN disclosed
WO-2017181008-A1 METHODS FOR IDENTIFYING MODULATORS OF GPR92 MARS, INCORPORATED (US) 2017-10-19 WO disclosed
EP-1613298-A4 LYSOPHOSPHATIDIC ACID ANALOGS AND INHIBITION OF NEOINTIMA FORMATION UNIV TENNESSEE RES FOUNDATION (US) 2007-10-03 EP disclosed
EP-1613298-A2 LYSOPHOSPHATIDIC ACID ANALOGS AND INHIBITION OF NEOINTIMA FORMATION The University of Tennessee Research Foundation (US) 2006-01-11 EP disclosed
WO-2004091496-A2 LYSOPHOSPHATIDIC ACID ANALOGS AND INHIBITION OF NEOINTIMA FORMATION THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2004-10-28 WO disclosed
US-20040204383-A1 Lysophosphatidic acid analogs and inhibition of neointima formation UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE 2004-10-14 US disclosed