Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PGD | P52209 | 3/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033517 | 1.00 | PTPN1 (0.43) | PTPN1PGDMPILMNAL3MBTL1 | |
| SCHEMBL29431969 | 0.86 | LMNA (0.42) | PTPN1PGDMPILMNAL3MBTL1 | |
| SCHEMBL29408337 | 0.86 | LMNA (0.42) | PTPN1PGDMPILMNAL3MBTL1 | |
| SCHEMBL6470157 | 0.85 | PTPN1 (0.47) | PTPN1PGDMPILMNASMPD1 | |
| SCHEMBL27468464 | 0.85 | LMNA (0.46) | PTPN1LMNAL3MBTL1TDP1 | |
| SCHEMBL15954307 | 0.85 | PTPN1 (0.51) | PTPN1PGDMPISMPD1 | |
| SCHEMBL29886751 | 0.85 | LMNA (0.46) | PTPN1LMNAL3MBTL1TDP1 | |
| SCHEMBL8854308 | 0.83 | PTPN1 (0.41) | PTPN1PGDMPISMPD1TDP1 | |
| SCHEMBL15270851 | 0.83 | PGD (0.50) | PTPN1PGDMPIPGK1PGK2 | |
| SCHEMBL3744531 | 0.83 | PGD (0.46) | PTPN1PGDMPIPGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013133772-A1 | AN INTEGRATED SOLID PHASE EXTRACTION COUPLED ULTRA-PERFORMANCE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (SPE-UPLC-MS) METHOD FOR THE PROFILING OF DXP METABOLITES AND SYSTEM DIAGNOSTICS OF DXP PATHWAY | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2013-09-12 | — | — | WO | claimed |
| US-20140128289-A1 | METHODS OF PROMOTING WEIGHT LOSS AND ASSOCIATED ARRAYS | THE WASHINGTON UNIVERSITY (US) | 2014-05-08 | — | — | US | disclosed |
| WO-2013133772-A1 | AN INTEGRATED SOLID PHASE EXTRACTION COUPLED ULTRA-PERFORMANCE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (SPE-UPLC-MS) METHOD FOR THE PROFILING OF DXP METABOLITES AND SYSTEM DIAGNOSTICS OF DXP PATHWAY | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2013-09-12 | — | — | WO | disclosed |
| US-20110177976-A1 | METHODS FOR PROMOTING WEIGHT LOSS AND ASSOCIATED ARRAYS | THE WASHINGTON UNIVERSITY (US) | 2011-07-21 | — | — | US | disclosed |
| WO-2001083769-A9 | CRYSTALLIZATION OF 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL SYNTHESIS | SALK INST FOR BIOLOGICAL STUDI (US) | 2003-02-06 | — | — | WO | disclosed |
| EP-1198575-A1 | ISOPRENOID BIOSYNTHESIS | Bacher, Adelbert (DE) | 2002-04-24 | — | — | EP | disclosed |
| WO-2001083769-A2 | CRYSTALLIZATION OF 4-DIPHOSPHOCYTIDYL-2-C-METHYLERYTHRITOL SYNTHESIS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2001-11-08 | — | — | WO | disclosed |
| WO-2001011055-A1 | ISOPRENOID BIOSYNTHESIS | BACHER ADELBERT (DE) | 2001-02-15 | — | — | WO | disclosed |