Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.39 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5001522 | 0.87 | BMPR1B (0.43) | MEN1KMT2ACHRM1BMPR1BBMPR1A | |
| SCHEMBL29785238 | 0.85 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1POLBCHRM1 | |
| SCHEMBL2816698 | 0.85 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1POLBCHRM1 | |
| SCHEMBL5506028 | 0.77 | CHRM5 (0.48) | MEN1KMT2AALDH1A1CHRM1CHRM5 | |
| SCHEMBL5509026 | 0.75 | CES1 (0.39) | MEN1KMT2AALDH1A1POLBCHRM1 | |
| SCHEMBL5505549 | 0.75 | KMT2A (0.43) | MEN1KMT2AALDH1A1BMPR1BBMPR1A | |
| SCHEMBL8551856 | 0.72 | SRD5A1 (0.45) | MEN1KMT2ACHRM1HTR1A | |
| SCHEMBL5001527 | 0.70 | CHRM1 (0.39) | MEN1KMT2AALDH1A1CHRM1CASP3 | |
| SCHEMBL2078451 | 0.69 | BMPR1B (0.44) | ALDH1A1BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL30404908 | 0.69 | KMT2A (0.46) | MEN1KMT2AALDH1A1POLBCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781642-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016221-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |