Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 4/20 | 0.40 |
| ▸ | CMA1 | P23946 | 2/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.39 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 9/20 | 0.38 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505557 | 0.93 | EPHX2 (0.46) | EPHX2AHRCMA1GRIA1EIF2AK2 | |
| SCHEMBL2491904 | 0.79 | AHR (0.50) | EPHX2AHRCMA1GRIA1EIF2AK2 | |
| SCHEMBL5506438 | 0.78 | EPHX2 (0.46) | EPHX2AHRCMA1GRIA1EIF2AK2 | |
| SCHEMBL2486755 | 0.73 | GRIA1 (0.51) | EPHX2AHRCMA1GRIA1EIF2AK2 | |
| SCHEMBL11106607 | 0.73 | AHR (0.53) | AHRCMA1GRIA1EIF2AK2SMYD3 | |
| SCHEMBL31010750 | 0.72 | AHR (0.59) | EPHX2AHRCMA1GRIA1EIF2AK2 | |
| SCHEMBL5499322 | 0.72 | EPHX2 (0.39) | EPHX2AHRCMA1GRIA1EIF2AK2 | |
| SCHEMBL5498091 | 0.71 | PGR (0.43) | EPHX2AHRCMA1GRIA1EIF2AK2 | |
| SCHEMBL5499457 | 0.70 | AHR (0.42) | EPHX2AHRCMA1GRIA1EIF2AK2 | |
| SCHEMBL153860 | 0.69 | AHR (0.53) | EPHX2AHRCMA1GRIA1EIF2AK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781642-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016221-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |