Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 3/20 | 0.38 |
| ▸ | CMA1 | P23946 | 2/20 | 0.38 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 7/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499457 | 0.81 | AHR (0.42) | EPHX2AHRCMA1EIF2AK2SMYD3 | |
| SCHEMBL5501521 | 0.77 | PGR (0.40) | EPHX2AHRCMA1EIF2AK2GRIN1 | |
| SCHEMBL5504321 | 0.77 | GRIA1 (0.39) | EPHX2AHRCMA1EIF2AK2SMYD3 | |
| SCHEMBL5503888 | 0.77 | AHR (0.39) | EPHX2AHRCMA1EIF2AK2SMYD3 | |
| SCHEMBL2491904 | 0.76 | AHR (0.50) | EPHX2AHRCMA1EIF2AK2SMYD3 | |
| SCHEMBL5499443 | 0.76 | VDR (0.42) | EPHX2AHRCMA1EIF2AK2SMYD3 | |
| SCHEMBL5502616 | 0.74 | F10 (0.35) | GRIN1SMYD3 | |
| SCHEMBL5505557 | 0.74 | EPHX2 (0.46) | EPHX2AHRCMA1EIF2AK2SMYD3 | |
| SCHEMBL188979 | 0.74 | GRIA1 (0.37) | EPHX2AHRCMA1EIF2AK2SMYD3 | |
| SCHEMBL5502648 | 0.72 | EPHX2 (0.51) | EPHX2AHRCMA1EIF2AK2SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781643-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016220-A1 | OXINDOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |