Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095285 | 0.63 | HRH3 (0.39) | HRH3CA12CA1CA2CA9 | |
| SCHEMBL4386534 | 0.63 | CA12 (0.44) | HRH3MAPTCA12CA1CA2 | |
| SCHEMBL4385695 | 0.62 | HRH3 (0.45) | HRH3MAPTCA12CA1CA2 | |
| SCHEMBL13397351 | 0.61 | HRH3 (0.50) | HRH3MAPTCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL5910804 | 0.61 | HRH3 (0.62) | HRH3MAPTCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL19441786 | 0.60 | CARM1 (0.39) | HRH3MAPTCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL13397474 | 0.59 | HRH3 (0.46) | HRH3CYP2C19MAPTCYP1A2MAPK1 | |
| SCHEMBL5910757 | 0.59 | HRH3 (0.57) | HRH3MAPTCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL20333472 | 0.58 | HRH3 (0.56) | HRH3CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL154378 | 0.58 | MAPT (0.83) | HRH3MAPTCYP1A2MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |