Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.83 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150332 | 1.00 | MAPT (0.83) | MAPTPOLBHRH3ALDH1A1PKM | |
| SCHEMBL146416 | 0.98 | MAPT (0.86) | MAPTPOLBHRH3ALDH1A1PKM | |
| SCHEMBL151103 | 0.93 | MAPT (0.95) | MAPTPOLBHRH3ALDH1A1PKM | |
| SCHEMBL151720 | 0.93 | MAPT (0.95) | MAPTPOLBHRH3ALDH1A1PKM | |
| SCHEMBL27895291 | 0.93 | — | — | |
| SCHEMBL6738785 | 0.91 | MAPT (0.91) | MAPTPOLBHRH3ALDH1A1PKM | |
| SCHEMBL7228795 | 0.91 | MAPT (0.91) | MAPTPOLBHRH3ALDH1A1PKM | |
| SCHEMBL9322332 | 0.91 | MAPT (0.91) | MAPTPOLBHRH3ALDH1A1PKM | |
| SCHEMBL149979 | 0.91 | MAPT (1.00) | MAPTPOLBHRH3ALDH1A1PKM | |
| SCHEMBL9206204 | 0.88 | MAPT (0.95) | MAPTPOLBHRH3ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210904-B1 | PHENYL-(3-HEXAMETHYLENE IMINOPROPYL) KETONE, PROCESS FOR ITS PREPARATION AND THERAPEUTICAL USE | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1989-09-06 | — | — | EP | claimed |
| EP-0110748-B1 | DERIVATIVES OF PHENYL-(3-AMINOPROPYL) KETONE, THEIR THERAPEUTICAL USE AND PROCESS FOR THEIR PREPARATION | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1987-04-22 | — | — | EP | claimed |
| EP-0210904-A1 | Phenyl-(3-hexamethylene iminopropyl) ketone, process for its preparation and therapeutical use | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1987-02-04 | — | — | EP | claimed |
| EP-0110748-A1 | Derivatives of phenyl-(3-aminopropyl) ketone, their therapeutical use and process for their preparation | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1984-06-13 | — | — | EP | claimed |
| US-9469710-B2 | Polymers functionalized with nitrile compounds containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2016-10-18 | — | — | US | disclosed |
| CN-103333275-B | With the polymkeric substance of functionalized with nitrile compounds comprising protected amino | BRIDGESTONE CO., LTD. (JP) | 2015-07-29 | — | — | CN | disclosed |
| US-20150148489-A1 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2015-05-28 | — | — | US | disclosed |
| US-8735494-B2 | Polymers functionalized with nitrile compounds containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2014-05-27 | — | — | US | disclosed |
| CN-103333275-A | Polymers functionalized with nitrile compounds containing a protected amino group | BRIDGESTONE CORP | 2013-10-02 | — | — | CN | disclosed |
| CN-102361887-B | Polymers functionalized with nitrile compounds containing a protected amino group | BRIDGESTONE CORP | 2013-06-26 | — | — | CN | disclosed |
| US-20130085227-A1 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2013-04-04 | — | — | US | disclosed |
| US-8344066-B2 | Polymers functionalized with nitrile compounds containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20070190041-A1 | Novel benzothiazepine and bensothiepine compounds | ASHAI KASEI PHARAMA CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20040176361-A1 | Fused heterocyclic compound and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2004-09-09 | — | — | US | disclosed |
| EP-1396488-A1 | FUSED HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2004-03-10 | — | — | EP | disclosed |
| EP-0210904-B1 | PHENYL-(3-HEXAMETHYLENE IMINOPROPYL) KETONE, PROCESS FOR ITS PREPARATION AND THERAPEUTICAL USE | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1989-09-06 | — | — | EP | disclosed |
| US-4758560-A | Phenyl-(3-hexamethyleneiminopropyl)-ketone | SOCIETE ANONYME DITE: LABORATOIRE L. LAFON (FR) | 1988-07-19 | — | — | US | disclosed |
| EP-0110748-B1 | DERIVATIVES OF PHENYL-(3-AMINOPROPYL) KETONE, THEIR THERAPEUTICAL USE AND PROCESS FOR THEIR PREPARATION | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1987-04-22 | — | — | EP | disclosed |
| EP-0210904-A1 | Phenyl-(3-hexamethylene iminopropyl) ketone, process for its preparation and therapeutical use | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1987-02-04 | — | — | EP | disclosed |
| EP-0110748-A1 | Derivatives of phenyl-(3-aminopropyl) ketone, their therapeutical use and process for their preparation | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1984-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176361-A1 | Fused heterocyclic compound and medicinal use thereof | PARP11, PARP1, CD38 | MAPT 1241/4885POLB 784/4885HRH3 2016/4885 |
| US-20070190041-A1 | Novel benzothiazepine and bensothiepine compounds | SLC10A1, GOT1, CES1 | MAPT 2335/4885POLB 4164/4885HRH3 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.