Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104871 | 0.74 | HPGD (0.40) | HRH3LMNAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL8104861 | 0.73 | HRH3 (0.34) | HRH3CARM1PRMT6PRMT8LMNA | |
| SCHEMBL5910804 | 0.66 | HRH3 (0.62) | HRH3ALDH1A1SMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL11214291 | 0.64 | CARM1 (0.46) | HRH3CA12CA1CA2CA9 | |
| SCHEMBL5910757 | 0.64 | HRH3 (0.57) | HRH3CARM1PRMT6PRMT8SMN1; SMN2 | |
| SCHEMBL13661585 | 0.63 | HRH3 (0.56) | HRH3CA12CA1CA2CA9 | |
| SCHEMBL20333472 | 0.63 | HRH3 (0.56) | HRH3SMN1; SMN2CYP1A2MAPK1TSHR | |
| SCHEMBL7649376 | 0.63 | HRH3 (0.56) | HRH3SMN1; SMN2CYP1A2MAPK1SIGMAR1 | |
| SCHEMBL23828672 | 0.62 | HRH3 (0.81) | HRH3CARM1PRMT6PRMT8ALDH1A1 | |
| SCHEMBL4519052 | 0.62 | HRH3 (0.81) | HRH3CARM1PRMT6PRMT8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015814-A | Quinazoline derivative | ZENECA LIMITED (GB) | 2000-01-18 | — | — | US | disclosed |