SCHEMBL5502805

SCHEMBL5502805

CC1CCCN(CCN2[C]N(CCCN3CCC[C@@H]3C)CC2)C1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 10/20 0.36
KDM4E B2RXH2 2/20 0.35
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
CXCR4 P61073 3/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5505202 0.96 HRH3 (0.39) HRH3KDM4ECHRM2CHRM1
SCHEMBL5501715 0.89 HRH3 (0.34) HRH3CXCR4
SCHEMBL5502174 0.89 HRH3 (0.44) HRH3CXCR4
SCHEMBL5505523 0.85 HRH3 (0.41) HRH3CXCR4
SCHEMBL5505798 0.85 HRH3 (0.41) HRH3CXCR4
SCHEMBL5506424 0.85 HRH3 (0.41) HRH3CXCR4
SCHEMBL5508033 0.85 HRH3 (0.42) HRH3CXCR4
SCHEMBL5502044 0.85 HRH3 (0.35) HRH3CXCR4
SCHEMBL5507033 0.84 HRH3 (0.42) HRH3CXCR4
SCHEMBL5506016 0.83 CXCR4 (0.44) HRH3CXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1847530-A1 DIAMINE DERIVATIVE KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-10-24 EP disclosed