Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27526 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9152986 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL8917975 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL372448 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2504262 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL4332271 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6375256 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1975519 | 0.88 | — | — | |
| Bicarbonate SCHEMBL21925452 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6691301 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118562447-A | Preparation method of aluminum-doped cerium oxide nano abrasive | 内蒙古大学 | 2024-08-30 | — | — | CN | claimed |
| CN-118458819-A | High-entropy composite oxide and preparation method and application thereof | 西华师范大学 | 2024-08-09 | — | — | CN | claimed |
| CN-116899553-A | Cerium-zirconium-praseodymium-based composite material and preparation method and application thereof | 西华师范大学 | 2023-10-20 | — | — | CN | claimed |
| CN-116870894-A | Metal oxide composite material and one-step preparation method and application thereof | 西华师范大学 | 2023-10-13 | — | — | CN | claimed |
| CN-114177902-B | Cerium-zirconium solid solution with micron-sized macropores and preparation method and application thereof | 西华师范大学 | 2023-09-15 | — | — | CN | claimed |
| CN-114177902-A | Cerium-zirconium solid solution with micron-sized macropores and preparation method and application thereof | 西华师范大学 | 2022-03-15 | — | — | CN | claimed |
| CN-108821324-B | Nano cerium oxide and preparation method and application thereof | 珠海琴晟新材料有限公司 | 2020-05-19 | — | — | CN | claimed |
| CN-119786592-A | Positive electrode material, preparation method thereof, positive electrode plate and secondary battery | 五邑大学 | 2025-04-08 | — | — | CN | disclosed |
| US-20250083971-A1 | CERIUM (III) CARBONATE FORMULATIONS | UNIV CALIFORNIA (US) | 2025-03-13 | — | — | US | disclosed |
| CN-119081653-B | Preparation method and application of dopamine hydrochloride modified cerium oxide core-shell abrasive | 内蒙古大学 | 2025-01-24 | — | — | CN | disclosed |
| US-12180084-B2 | Cerium (III) carbonate formulations | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-12-31 | — | — | US | disclosed |
| CN-119081653-A | Preparation method and application of dopamine hydrochloride modified cerium oxide core-shell abrasive | 内蒙古大学 | 2024-12-06 | — | — | CN | disclosed |
| CN-118562447-B | Preparation method of aluminum-doped cerium oxide nano abrasive | 内蒙古大学 | 2024-10-18 | — | — | CN | disclosed |
| WO-2020219674-A1 | CERIUM (III) CARBONATE FORMULATIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-10-29 | — | — | WO | disclosed |
| CN-108821324-B | Nano cerium oxide and preparation method and application thereof | 珠海琴晟新材料有限公司 | 2020-05-19 | — | — | CN | disclosed |
| EP-2260013-B1 | CERIA MATERIAL AND METHOD OF FORMING SAME | SAINT GOBAIN CERAMICS (US) | 2018-12-19 | — | — | EP | disclosed |
| US-20070240366-A1 | Composition for Polishing | NISSAN CHEMICAL INDUSTRIES, LTD (JP) | 2007-10-18 | — | — | US | disclosed |
| EP-1747849-A1 | COMPOSITION FOR POLISHING | Nissan Chemical Industries, Ltd. (JP) | 2007-01-31 | — | — | EP | disclosed |
| JP-2003252622-A | PRODUCTION METHOD FOR NANO ACICULAR CERIA POWDER | NATIONAL INSTITUTE FOR MATERIALS SCIENCE | 2003-09-10 | — | — | JP | disclosed |
| JP-2003020224-A | METHOD FOR MANUFACTURING CERIA POWDER IN WHICH INDIVIDUAL PARTICLES ARE SEPARATED INTO NANOSIZE | NATIONAL INSTITUTE FOR MATERIALS SCIENCE | 2003-01-24 | — | — | JP | disclosed |