Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2002042 | 0.83 | TSHR (0.39) | EPHX2TSHRSMN1; SMN2 | |
| SCHEMBL2008356 | 0.79 | HPGD (0.33) | SMN1; SMN2GRIN1GRIN2B | |
| SCHEMBL2002994 | 0.75 | HDAC8 (0.45) | EPHX2 | |
| SCHEMBL2002991 | 0.75 | HDAC8 (0.45) | EPHX2 | |
| SCHEMBL2952173 | 0.75 | KDM4E (0.47) | — | |
| SCHEMBL5509255 | 0.73 | ALDH1A1 (0.44) | EPHX2NR1H4 | |
| SCHEMBL2001037 | 0.72 | NSD2 (0.39) | — | |
| SCHEMBL1999920 | 0.72 | TSHR (0.41) | EPHX2TSHRSMN1; SMN2 | |
| SCHEMBL2003822 | 0.69 | EPHX2 (0.53) | EPHX2NR1H4 | |
| SCHEMBL5313569 | 0.67 | EPHX2 (0.61) | EPHX2NR1H4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861358-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Amorepacific Corporation (KR) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006101321-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2006-09-28 | — | — | WO | disclosed |