Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192379 | 0.96 | PPARG (0.46) | — | |
| SCHEMBL9197447 | 0.93 | — | — | |
| SCHEMBL9194925 | 0.91 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9198023 | 0.90 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9197454 | 0.89 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9196961 | 0.88 | — | — | |
| SCHEMBL166867 | 0.88 | AGTR2 (0.56) | AGTR1AGTR2 | |
| SCHEMBL7015090 | 0.88 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL3975130 | 0.86 | AGTR2 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9192698 | 0.86 | AGTR1 (0.50) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425921-B1 | Benzimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-09 | — | — | EP | claimed |
| US-5128356-A | Angiotensin antagonist; cardiovascular disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-07-07 | — | — | US | claimed |
| EP-0425921-A1 | Benzimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-05-08 | — | — | EP | claimed |
| EP-1844774-A2 | A pharmaceutical composition for angiotensin II-mediated diseases | Takeda Pharmaceutical Company Limited (JP) | 2007-10-17 | — | — | EP | disclosed |
| EP-1306088-B1 | Combination of a benzimidazole having angiotensin-II antagonistic activity with a diuretic | TAKEDA PHARMACEUTICAL (JP) | 2007-09-05 | — | — | EP | disclosed |
| EP-1306089-B1 | Combination of benzimidazoles having angiotensin-II antagonistic activity with diuretics | TAKEDA PHARMACEUTICAL (JP) | 2007-09-05 | — | — | EP | disclosed |
| EP-1468683-A2 | Pharmaceutical composition for oral use with angiotensin-II-antagonistic activity and method of preparing it | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-10-20 | — | — | EP | disclosed |
| EP-0782852-B1 | Pharmaceutical compositions of heterocyclic angiotensin-II antagonists and oily substances for oral use and method of preparing them | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| EP-1306089-A1 | Combination of benzimidazoles having angiotensin-II antagonistic activity with diuretics or calcium antagonists | Takeda Chemical Industries, Ltd. (JP) | 2003-05-02 | — | — | EP | disclosed |
| EP-1306088-A1 | Combination of a benzimidazole having angiotensin-II antagonistic activity with a diuretic | Takeda Chemical Industries, Ltd. (JP) | 2003-05-02 | — | — | EP | disclosed |
| EP-0668272-B1 | A process for the production of tetrazolyl compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-07-12 | — | — | EP | disclosed |
| US-5578733-A | REACTION WITH MINERAL ACID IN THE PRESENCE OF ALCOHOL TO REMOVE PROTECTIVE GROUP | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0668272-A2 | A process for the production of tetrazolyl compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-23 | — | — | EP | disclosed |
| EP-0425921-B1 | Benzimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-09 | — | — | EP | disclosed |
| WO-1995001176-A1 | USE OF AN ANGIOTENSIN II ANTAGONIST AS AN OCULAR HYPOTENSIVE AGENT | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |
| EP-0631780-A1 | Use of an angiotensin II antagonist as an ocular hypotensive agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-01-04 | — | — | EP | disclosed |
| EP-0628313-A1 | Combination of benzimidazoles having angiotensin-II antagonistic activity with dinretics or calcium antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-14 | — | — | EP | disclosed |
| EP-0622077-A1 | Angiotensin II antagonists as a prophylactic or therapeutic drug for renal diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-11-02 | — | — | EP | disclosed |
| US-5128356-A | Angiotensin antagonist; cardiovascular disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0425921-A1 | Benzimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-05-08 | — | — | EP | disclosed |