Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 12/20 | 0.46 |
| ▸ | AR | P10275 | 4/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3853342 | 0.96 | CCR1 (0.48) | CCR1ARCCR3 | |
| SCHEMBL3850884 | 0.94 | AR (0.50) | CCR1ARNOS3NOS1NOS2 | |
| SCHEMBL5511464 | 0.82 | CCR1 (0.42) | CCR1 | |
| SCHEMBL3856508 | 0.82 | CCR1 (0.46) | CCR1AR | |
| SCHEMBL3860327 | 0.81 | DRD2 (0.57) | CCR1CCR3 | |
| SCHEMBL3854368 | 0.79 | AR (0.42) | CCR1ARNOS3NOS1NOS2 | |
| SCHEMBL3854549 | 0.79 | OPRM1 (0.48) | CCR1AR | |
| SCHEMBL3852309 | 0.78 | DRD2 (0.54) | CCR1 | |
| SCHEMBL3851778 | 0.78 | DRD2 (0.52) | CCR1 | |
| SCHEMBL3859083 | 0.76 | CCR1 (0.44) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765779-A1 | NEW SUBSTITUTED PIPERIDINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005121092-A1 | NEW SUBSTITUTED PIPERIDINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | disclosed |