Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | GPR142 | Q7Z601 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565308 | 0.78 | KDM4E (0.44) | SLC6A3SLC6A2SLC6A4GPR142CAPN1 | |
| SCHEMBL7280731 | 0.77 | CYP1A2 (0.61) | SLC6A3GPR142FOLH1 | |
| SCHEMBL7829956 | 0.76 | PTPRA (0.65) | SLC6A4POLBCYP2C19P4HTMEPHX1 | |
| SCHEMBL7829954 | 0.76 | PTPRA (0.65) | SLC6A4POLBCYP2C19P4HTMEPHX1 | |
| SCHEMBL14561302 | 0.73 | GPR142 (0.40) | SLC6A3GPR142CAPN1CTSBCTSS | |
| SCHEMBL22193474 | 0.73 | GPR142 (0.40) | SLC6A3SLC6A2SLC6A4GPR142CAPN1 | |
| SCHEMBL6897379 | 0.73 | GPR142 (0.40) | SLC6A3SLC6A2SLC6A4GPR142CAPN1 | |
| SCHEMBL990477 | 0.73 | DPP4 (0.49) | SLC6A3GPR142POLBOPRD1 | |
| SCHEMBL6897376 | 0.73 | GPR142 (0.40) | SLC6A3SLC6A2SLC6A4GPR142CAPN1 | |
| SCHEMBL5535517 | 0.73 | GPR142 (0.40) | SLC6A3GPR142CAPN1CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786792-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | Astellas Pharma Inc. (JP) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006011631-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | ASTELLAS PHARMA INC. (JP) | 2006-02-02 | — | — | WO | disclosed |