SCHEMBL990477

SCHEMBL990477

N[C@@H](Cc1cscn1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.49
DPP8 Q6V1X1 2/20 0.49
DPP9 Q86TI2 2/20 0.49
CYP1A2 P05177 1/20 0.46
OPRD1 P41143 1/20 0.44
SLC7A5 Q01650 3/20 0.43
PKM P14618 2/20 0.43
ALPI P09923 1/20 0.43
PTGS1 P23219 1/20 0.43
XIAP P98170 1/20 0.43
KDM4E B2RXH2 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CYP3A4 P08684 2/20 0.40
GPR142 Q7Z601 1/20 0.40
USP2 O75604 2/20 0.40
SLC6A3 Q01959 1/20 0.40
RGS12 O14924 1/20 0.40
CYP2C9 P11712 1/20 0.40
ALOX15 P16050 1/20 0.40
NFKB1 P19838 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5907044 1.00 DPP4 (0.49) DPP4DPP8DPP9CYP1A2OPRD1
SCHEMBL990478 1.00 DPP4 (0.49) DPP4DPP8DPP9CYP1A2OPRD1
Hydrochloric Acid SCHEMBL5733961 0.98 DPP4 (0.48) DPP4DPP8DPP9CYP1A2OPRD1
Hydrochloric Acid SCHEMBL7300435 0.98 DPP4 (0.48) DPP4DPP8DPP9CYP1A2OPRD1
Hydrochloric Acid SCHEMBL10867215 0.98 DPP4 (0.48) DPP4DPP8DPP9CYP1A2OPRD1
Hydrochloric Acid SCHEMBL5733967 0.98 DPP4 (0.48) DPP4DPP8DPP9CYP1A2OPRD1
Serine SCHEMBL3839203 0.94 DPP4 (0.45) DPP4DPP8DPP9CYP1A2OPRD1
Trifluoroacetic Acid SCHEMBL5735676 0.91 GRB2 (0.46) DPP4DPP8DPP9CYP1A2OPRD1
SCHEMBL3839201 0.86 DPP4 (0.43) DPP4DPP8DPP9CYP1A2OPRD1
SCHEMBL5207691 0.86 DPP4 (0.49) DPP4DPP8DPP9OPRD1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 726 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP claimed
US-20250186539-A2 METHODS FOR TREATING CANCER BICYCLETX LIMITED (GB) 2025-06-12 US claimed
CN-118864883-B Audio-visual dance generation method and system based on diffusion model and cross-mode collaboration 浙江大学 2025-04-29 CN claimed
WO-2025051920-A1 NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR INHIBITORS SANOFI (FR) 2025-03-13 WO claimed
CN-119402531-A Ocean monitoring data processing method based on AI and Internet of things technology 青岛启弘信息科技有限公司 2025-02-07 CN claimed
CN-119334361-A High-precision stable aiming tracking error correction method for two-dimensional turntable 中国科学院西安光学精密机械研究所 2025-01-21 CN claimed
EP-4464715-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 BicycleTx Limited (GB) 2024-11-20 EP claimed
CN-118864883-A Audio-visual dance generation method and system based on diffusion model and cross-modal collaboration 浙江大学 2024-10-29 CN claimed
CN-118870391-A Wireless sensor network gateway optimization method and system 深圳市奇特龙科技有限公司 2024-10-29 CN claimed
US-20240325554-A1 METHODS FOR TREATING CANCER BICYCLE TX LTD (GB) 2024-10-03 US claimed
WO-2021019245-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EphA2 BICYCLETX LIMITED (GB) 2021-02-04 WO claimed
WO-2021019246-A1 HETEROTANDEM BICYCLIC PEPTIDE COMPLEXES BICYCLETX LIMITED (GB) 2021-02-04 WO claimed
US-20200247858-A1 AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF FOG PHARMACEUTICALS, INC. (US) 2020-08-06 US claimed
EP-3678683-A2 AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF Fog Pharmaceuticals, Inc. (US) 2020-07-15 EP claimed
CN-111372942-A β -catenin function modulating agents and methods thereof 弗格制药有限公司 2020-07-03 CN claimed
WO-2019243832-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 BICYCLETX LIMITED (GB) 2019-12-26 WO claimed
US-10329321-B2 Site-selective functionalization of proteins using traceless affinity labels Krantz, Alexander (US) 2019-06-25 US claimed
WO-2019051327-A2 AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF FOG PHARMACEUTICALS, INC. (US) 2019-03-14 WO claimed
EP-3413921-A1 SITE-SELECTIVE FUNCTIONALIZATION OF PROTEINS USING TRACELESS AFFINITY LABLES Krantz, Alexander (US) 2018-12-19 EP claimed
WO-2017139329-A1 SITE-SELECTIVE FUNCTIONALIZATION OF PROTEINS USING TRACELESS AFFINITY LABLES KRANTZ ALEXANDER (US) 2017-08-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240325554-A1 METHODS FOR TREATING CANCER CD44, TUBB4A, TUBB3 DPP4 2226/4885DPP8 4128/4885DPP9 3621/4885
US-20200247858-A1 AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF CTNNB1, CTNNBL1, CTNNA1 DPP4 616/4885DPP8 268/4885DPP9 283/4885
US-10329321-B2 Site-selective functionalization of proteins using traceless affinity labels MYCBP, FABP3, STUB1 DPP4 4207/4885DPP8 3410/4885DPP9 4104/4885
US-20250186539-A2 METHODS FOR TREATING CANCER CD44, TUBB4A, TUBB3 DPP4 2226/4885DPP8 4128/4885DPP9 3621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.