Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9928483 | 0.79 | KDM4E (0.50) | KDM4EMAPTHPGDALDH1A1GLA | |
| SCHEMBL10737174 | 0.79 | KDM4E (0.46) | KDM4EMAPTHPGDALDH1A1GLA | |
| SCHEMBL7807396 | 0.75 | CNR2 (0.47) | KDM4EMAPTHPGDALDH1A1GLA | |
| SCHEMBL7802446 | 0.75 | HPGD (0.45) | KDM4EMAPTHPGDALDH1A1GLA | |
| SCHEMBL11484120 | 0.73 | BACE1 (0.41) | KDM4EMAPTHPGDALDH1A1GLA | |
| SCHEMBL11173734 | 0.73 | ALDH1A1 (0.52) | KDM4EMAPTHPGDALDH1A1GLA | |
| SCHEMBL30248459 | 0.73 | ALDH1A1 (0.52) | KDM4EMAPTHPGDALDH1A1GLA | |
| SCHEMBL21451306 | 0.72 | BACE1 (0.41) | KDM4EMAPTHPGDALDH1A1ACHE | |
| Hydrochloric Acid SCHEMBL21979894 | 0.71 | ALDH1A1 (0.50) | KDM4EMAPTHPGDALDH1A1GLA | |
| SCHEMBL5483645 | 0.70 | ALDH1A1 (0.55) | KDM4EMAPTHPGDALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853566-A1 | CINNOLINE COMPOUNDS AND THEIR USE AS LIVER X RECEPTOR MODULATORS | Wyeth (US) | 2007-11-14 | — | — | EP | claimed |
| WO-2006094034-A1 | CINNOLINE COMPOUNDS AND THEIR USE AS LIVER X RECEPTOR MODILATORS | WYETH (US) | 2006-09-08 | — | — | WO | claimed |
| CN-113039237-B | Polyimide film, polyimide composition, and method for producing film using same | 株式会社东进世美肯 | 2023-12-15 | — | — | CN | disclosed |
| CN-114630825-A | Pesticidally active fused bicyclic heteroaromatic compounds | 先正达农作物保护股份公司 | 2022-06-14 | — | — | CN | disclosed |
| EP-1853566-A1 | CINNOLINE COMPOUNDS AND THEIR USE AS LIVER X RECEPTOR MODULATORS | Wyeth (US) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006094034-A1 | CINNOLINE COMPOUNDS AND THEIR USE AS LIVER X RECEPTOR MODILATORS | WYETH (US) | 2006-09-08 | — | — | WO | disclosed |