Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9928483 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1GLAMAPTHPGD | |
| SCHEMBL5503119 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1GLAMAPTHPGD | |
| SCHEMBL2781561 | 0.71 | KDM4E (0.50) | KDM4EALDH1A1GLAMAPTHPGD | |
| SCHEMBL276035 | 0.71 | ALDH1A1 (0.50) | KDM4EALDH1A1GLAMAPTHPGD | |
| SCHEMBL5483645 | 0.70 | ALDH1A1 (0.55) | KDM4EALDH1A1GLAMAPTHPGD | |
| SCHEMBL31115164 | 0.70 | ALDH1A1 (0.55) | KDM4EALDH1A1GLAMAPTHPGD | |
| SCHEMBL3294200 | 0.70 | NCF1 (0.46) | KDM4EALDH1A1GLAMAPTHPGD | |
| SCHEMBL31665931 | 0.70 | NCF1 (0.46) | KDM4EALDH1A1GLAMAPTHPGD | |
| SCHEMBL3293579 | 0.69 | L3MBTL1 (0.41) | KDM4EALDH1A1GLAMAPTHPGD | |
| SCHEMBL11173734 | 0.69 | ALDH1A1 (0.52) | KDM4EALDH1A1GLAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-86105084-A | HERBICIDAL CINNOLINE COMPOUNDS | — | 1987-04-29 | — | — | CN | claimed |
| EP-0212726-A2 | Herbicidal cinnoline compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-03-04 | — | — | EP | claimed |
| US-4699651-A | Use of certain cinnoline-4-carboxylic acids and congeners thereof for controlling the growth of unwanted plants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-10-13 | — | — | US | disclosed |
| CN-86105084-A | HERBICIDAL CINNOLINE COMPOUNDS | — | 1987-04-29 | — | — | CN | disclosed |
| EP-0212726-A2 | Herbicidal cinnoline compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-03-04 | — | — | EP | disclosed |