Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2920169 | 1.00 | NPC1 (0.39) | NPC1FKBP1ACYP2C9ALDH1A1KMT2A | |
| SCHEMBL2922625 | 0.94 | FKBP1A (0.38) | NPC1FKBP1ACYP2C9ALDH1A1KMT2A | |
| SCHEMBL2915001 | 0.94 | FKBP1A (0.38) | NPC1FKBP1ACYP2C9ALDH1A1KMT2A | |
| SCHEMBL2916459 | 0.94 | FKBP1A (0.38) | NPC1FKBP1ACYP2C9ALDH1A1KMT2A | |
| SCHEMBL2916456 | 0.94 | FKBP1A (0.38) | NPC1FKBP1ACYP2C9ALDH1A1KMT2A | |
| SCHEMBL2919792 | 0.93 | FKBP1A (0.37) | NPC1FKBP1ACYP2C9ALDH1A1KMT2A | |
| SCHEMBL2913268 | 0.93 | KMT2A (0.37) | NPC1FKBP1ACYP2C9ALDH1A1KMT2A | |
| SCHEMBL3466714 | 0.93 | RORC (0.36) | FKBP1ACYP2C9ALDH1A1KMT2ARORC | |
| SCHEMBL2924072 | 0.93 | FKBP1A (0.36) | NPC1FKBP1ACYP2C9ALDH1A1KMT2A | |
| SCHEMBL2922405 | 0.93 | FKBP1A (0.36) | NPC1FKBP1ACYP2C9ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863803-A2 | SUBSTITUTED PIPERIDINES | Speedel Experimenta AG (CH) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006103277-A2 | 2 , 4 , 5-SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | SPEEDEL EXPERIMENTA AG (CH) | 2006-10-05 | — | — | WO | disclosed |