Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6365588 | 0.88 | MAPT (0.59) | MEN1KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL3037389 | 0.85 | MEN1 (0.56) | MEN1KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL1169501 | 0.85 | KMT2A (0.56) | MEN1KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL3601229 | 0.84 | KMT2A (0.68) | MEN1KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL4785110 | 0.83 | TDP1 (0.61) | MEN1KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL18469618 | 0.83 | TDP1 (0.61) | MEN1KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL3056083 | 0.82 | MLYCD (0.63) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL18469616 | 0.82 | TDP1 (0.60) | MEN1KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL18469619 | 0.82 | TDP1 (0.60) | MEN1KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL4785358 | 0.82 | ALDH1A1 (0.57) | MEN1KMT2ATDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748985-A1 | CYCLIC AMIDE DERIVATIVES, AND THEIR PRODUCTION AND USE AS ANTITHROMBOTIC AGENTS | Takeda Pharmaceutical Company Limited (JP) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005113504-A1 | CYCLIC AMIDE DERIVATIVES, AND THEIR PRODUCTION AND USE AS ANTITHROMBOTIC AGENTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-12-01 | — | — | WO | disclosed |