SCHEMBL550353

SCHEMBL550353

Cc1ncc(C=O)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13574820 0.76
SCHEMBL12151092 0.76
SCHEMBL17099921 0.75 ALDH1A1 (0.48)
SCHEMBL20880240 0.74
SCHEMBL22723764 0.74
SCHEMBL15009344 0.74 CYP2E1 (0.47)
SCHEMBL30957 0.73
SCHEMBL13877137 0.73 TDP1 (0.44)
SCHEMBL360323 0.71
SCHEMBL22577271 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024552-A Small molecular antibacterial polypeptide, preparation method and application thereof 深圳碳云智肽药物科技有限公司 2023-11-10 CN claimed
CN-116947999-A Small molecular antibacterial polypeptide, preparation method and application thereof 深圳碳云智肽药物科技有限公司 2023-10-27 CN claimed
CN-110088103-B Novel tetrahydropyridopyrimidine compounds for the treatment and prophylaxis of hepatitis b virus infection 豪夫迈·罗氏有限公司 2022-04-12 CN claimed
EP-3464321-A1 PROTEASOME INHIBITORS Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2019-04-10 EP claimed
WO-2017211818-A1 PROTEASOME INHIBITORS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2017-12-14 WO claimed
EP-4695242-A1 NOVEL SUBSTITUTED PYRROLE COMPOUNDS, COMPOSITIONS COMPRISING THE SUBSTITUTED PYRROLE COMPOUND, AND METHODS OF USE THEREOF Meta Pharmaceuticals (HK) Limited (HK) 2026-02-18 EP disclosed
EP-4673137-A1 NBD1 MODULATORS AND METHODS OF USING THE SAME Sionna Therapeutics Inc. (US) 2026-01-07 EP disclosed
US-12479797-B2 Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors Jubilant Epicore LLC (US) 2025-11-25 US disclosed
EP-3455204-B1 CYCLOPROPYL-AMIDE COMPOUNDS AS DUAL LSD1/HDAC INHIBITORS Jubilant Epicore LLC (US) 2025-10-29 EP disclosed
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 US disclosed
US-20250145601-A1 NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS SATYA THERAPEUTICS, INC. 2025-05-08 US disclosed
US-4551457-A GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS FARMITALIA CARLO ERBA, S.P.A. (IT) 1985-11-05 US disclosed
EP-0125094-A2 Herbicidal cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1984-11-14 EP disclosed
EP-0034481-B1 2-METHYL-5-THIAZOLE-METHYLAMINE AND CARBOXAMIDE DERIVATIVES Grigg, Ronald Ernest (GB) 1984-05-30 EP disclosed
US-4444773-A ANTIULCER, ANTISECRETORY, ANTIINFLAMMATORY FARMITALIA CARLO ERBA S.P.A. (IT) 1984-04-24 US disclosed
US-4172137-A 5-Thiazole-alkylamines used as antilipolytics ROUSSEL UCLAF (FR) 1979-10-23 US disclosed
US-4073919-A Hypolipemiant compositions and methods ROUSSEL UCLAF (FR) 1978-02-14 US disclosed
US-4053618-A ANTILIPOLYTIC ROUSSEL-UCLAF (FR) 1977-10-11 US disclosed
US-4032643-A ANTILIPOLYTIC AGENTS, VASODILATION, ANTIBRADYKINETIC AGENTS ROUSSEL-UCLAF (FR) 1977-06-28 US disclosed