⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352088 | 0.67 | — | — | |
| SCHEMBL179932 | 0.67 | CHKA (0.33) | — | |
| SCHEMBL3376945 | 0.55 | — | — | |
| SCHEMBL1157246 | 0.55 | — | — | |
| SCHEMBL13661859 | 0.53 | KDM4E (0.36) | — | |
| SCHEMBL5601494 | 0.52 | LMNA (0.33) | — | |
| SCHEMBL7856072 | 0.51 | — | — | |
| SCHEMBL1077579 | 0.50 | — | — | |
| SCHEMBL3945064 | 0.50 | — | — | |
| SCHEMBL3262365 | 0.49 | MAPK1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498290-B1 | Pyridobenzodiazepines, dipyrido [3,2-b:2',3'-e] [1,4]diazepines and their use in the prevention or treatment of HIV infection | BOEHRINGER INGELHEIM PHARMA (US) | 1996-09-18 | — | — | EP | claimed |
| EP-0498290-A1 | Pyridobenzodiazepines, dipyrido [3,2-b:2',3'-e] [1,4]diazepines and their use in the prevention or treatment of HIV infection | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1992-08-12 | — | — | EP | claimed |
| US-20070191413-A1 | Novel heterocycle-substituted hydroxy-6-phenylphenanthridines and their use as pde4 inhibitors | ATLANTA PHARMA AG (DE) | 2007-08-16 | — | — | US | disclosed |
| EP-1812400-A1 | NOVEL HETEROCYCLYL-SUBSTITUTED HYDROXY-6-PHENYLPHENANTHRIDINES AND THEIR USE AS PDE4 INHIBITORS | Altana Pharma AG (DE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2005090311-A1 | NOVEL HETEROCYCLYL-SUBSTITUTED HYDROXY-6-PHENYLPHENANTHRIDINES AND THEIR USE AS PDE4 INHIBITORS | ALTANA PHARMA AG (DE) | 2005-09-29 | — | — | WO | disclosed |
| US-5459142-A | Autoimmune disease, atherosclerosis, antiischemic agents and nephritis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-10-17 | — | — | US | disclosed |
| EP-0511879-B1 | Pyrazine derivatives | OTSUKA PHARMA CO LTD (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-5213958-A | SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL CONTAINING A PHOTOGRAPHIC YELLOW DYE FORMING COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |
| EP-0482552-A1 | Silver halide color photographic photosensitive materials | Fuji Photo Film Co., Ltd. (JP) | 1992-04-29 | — | — | EP | disclosed |