Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5602957 | 0.98 | MAPK1 (0.32) | LMNAMAPT | |
| SCHEMBL5603589 | 0.98 | MAPK1 (0.32) | LMNAMAPT | |
| SCHEMBL5602657 | 0.98 | MAPK1 (0.32) | LMNAMAPT | |
| SCHEMBL5601172 | 0.98 | MAPK1 (0.32) | LMNAMAPT | |
| SCHEMBL5600749 | 0.93 | LMNA (0.37) | LMNAMAPT | |
| SCHEMBL2073935 | 0.73 | CYP11B2 (0.42) | LMNAMAPTALDH1A1 | |
| SCHEMBL11815703 | 0.70 | MAPT (0.43) | LMNAMAPTALDH1A1KDM1A | |
| SCHEMBL5718185 | 0.70 | — | — | |
| SCHEMBL29780367 | 0.68 | MAPT (0.37) | LMNAMAPTALDH1A1KDM1A | |
| SCHEMBL497034 | 0.68 | MAPT (0.37) | LMNAMAPTALDH1A1HPGDKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| CN-103288710-A | Preparation method of trandolapril midbody (2S, 3aR, 7aS)-octahydro-1H-indole-2-carboxylic acid | DALIAN HAIRONG TECHNOLOGY DEV CO LTD | 2013-09-11 | — | — | CN | disclosed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |
| EP-0248393-B1 | METHOD FOR THE PREPARATION OF ACYLATED HETEROAROMATICS AT ZEOLITHIC CATALYSTS | BASF Aktiengesellschaft (DE) | 1991-08-07 | — | — | EP | disclosed |