Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16638093 | 0.84 | L3MBTL1 (0.49) | L3MBTL1MAPTMAPK1GFERCYP1A2 | |
| SCHEMBL3821392 | 0.79 | L3MBTL1 (0.43) | L3MBTL1MAPTMAPK1GFERCYP1A2 | |
| SCHEMBL19899721 | 0.78 | L3MBTL1 (0.56) | L3MBTL1MAPTMAPK1CYP1A2CYP2C19 | |
| SCHEMBL27189175 | 0.77 | L3MBTL1 (0.54) | L3MBTL1MAPTCYP1A2CYP2C19NPC1 | |
| SCHEMBL21066336 | 0.77 | L3MBTL1 (0.54) | L3MBTL1MAPTMAPK1GFERCYP1A2 | |
| SCHEMBL10274884 | 0.77 | TLR7 (0.45) | MAPTMAPK1GFERNPC1RAB9A | |
| SCHEMBL5224240 | 0.77 | L3MBTL1 (0.54) | L3MBTL1MAPTMAPK1GFERCYP1A2 | |
| SCHEMBL14844533 | 0.75 | L3MBTL1 (0.51) | L3MBTL1MAPTMAPK1CYP1A2CYP2C19 | |
| SCHEMBL1691061 | 0.74 | MAPT (0.68) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21066367 | 0.74 | L3MBTL1 (0.51) | L3MBTL1MAPTMAPK1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791837-A1 | SUBSTITUTED HYDANTOINS FOR THE TREATMENT OF CANCER | F. Hoffmann-Roche AG (CH) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006029862-A1 | SUBSTITUTED HYDANTOINS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2006-03-23 | — | — | WO | disclosed |