Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844533 | 0.82 | L3MBTL1 (0.51) | L3MBTL1RAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL19899721 | 0.82 | L3MBTL1 (0.56) | L3MBTL1RAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL5224240 | 0.81 | L3MBTL1 (0.54) | L3MBTL1RAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL19914275 | 0.80 | PI4KB (0.47) | L3MBTL1RAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL2642829 | 0.80 | HIF1A (0.60) | RAB9ANPC1SMN1; SMN2TDP1MAPT | |
| SCHEMBL18595010 | 0.80 | ROCK2 (0.59) | RAB9ANPC1SMN1; SMN2HIF1AGAA | |
| SCHEMBL12676691 | 0.80 | GAA (0.43) | L3MBTL1RAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL13116110 | 0.80 | AMY1A (0.58) | RAB9ATDP1MAPTMAPK1GAA | |
| SCHEMBL163960 | 0.77 | HIF1A (0.42) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL2643525 | 0.76 | HIF1A (0.41) | L3MBTL1NPC1SMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | B3GNT2, RPN2, RPN1 | L3MBTL1 4525/4885RAB9A 1688/4885NPC1 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.