Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1860867 | 0.86 | DPP4 (0.52) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL1860871 | 0.86 | DPP4 (0.52) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL5503749 | 0.71 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL1866281 | 0.70 | REN (0.52) | — | |
| SCHEMBL5509831 | 0.70 | REN (0.52) | — | |
| SCHEMBL5505418 | 0.70 | MEN1 (0.43) | MEN1KMT2A | |
| SCHEMBL1865703 | 0.70 | REN (0.52) | — | |
| SCHEMBL5505794 | 0.70 | REN (0.52) | — | |
| SCHEMBL5503829 | 0.70 | REN (0.52) | — | |
| SCHEMBL5509449 | 0.70 | MEN1 (0.43) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807078-A1 | DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006042150-A1 | DIAMINOALKANE ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2006-04-20 | — | — | WO | disclosed |